Cell Culture Scientist, Small Scale Production (Plainville, MA)

Work Schedule

Environmental Conditions

Job Description

About the Role

The Small-Scale Cell Culture Scientist is a hands-on technical contributor in the Bioprocess Design Center (BDC) responsible for designing executing and documenting upstream cell culture experiments that generate high-quality technical evidence for Thermo Fisher Scientifics single-use bioprocessing technologies.

This role operates at the intersection of experimental biology and systems-level process design. The successful candidate will independently own small-scale cell culture studies translate experimental outcomes into actionable insights and support integrated workflow development across upstream unit operations. While primarily lab-focused the role requires strong communication skills and comfort engaging with cross-functional partners and customers.

Location:

This is an onsite position in Plainville Massachusetts. Residency within commuting distance is required. No relocation assistance will be provided.

Key Responsibilities

Experimental Design & Execution

• Independently design and execute small-scale upstream cell culture experiments (typically 2L50L) using single-use bioreactor systems.
• Incorporate process analytical techniques (PAT) online sensors and at-line/off-line analytics to monitor and assess cell culture performance.
• Execute mammalian cell culture processes such as fed-batch and intensified workflows ensuring reproducibility data integrity and traceability.
• Troubleshoot experimental and data-related issues including sensor performance data quality and process variability.

Systems Automation & PAT enablement

• Analyze experimental datasets using advanced data analytics approaches including multivariate analysis trend analysis and statistical methods as appropriate.
• Leverage JUMP and other analytical programs to support data-driven decision making and improve experimental efficiency.
• Translate complex datasets into clear defensible conclusions and visual summaries suitable for internal and customer-facing audiences.
• Author protocols technical reports summaries and SOPs that integrate experimental outcomes with process data insights.

Data Analysis & Digital Enablement

• Analyze experimental datasets using advanced data analytics approaches including multivariate analysis trend analysis and statistical methods as appropriate.
• Leverage JUMP and other analytical programs to support data-driven decision making and improve experimental efficiency.
• Translate complex datasets into clear defensible conclusions and visual summaries suitable for internal and customer-facing audiences.
• Author protocols technical reports summaries and SOPs that integrate experimental outcomes with process data insights.

Collaboration & Communication

• Collaborate closely with engineers scientists and cross-functional teams to align experimental work with BDC priorities.
• Support customer visits technical demonstrations and internal reviews by clearly explaining experimental intent and results.
• Communicate progress risks and outcomes effectively to technical and non-technical audiences.

Laboratory Operations & Compliance

• Maintain a safe compliant and organized laboratory environment.
• Follow applicable safety quality and data integrity requirements.
• Contribute to continuous improvement of lab workflows and experimental practices.

Qualifications

Education

• B.S. in Chemical Engineering Biochemical Engineering Biotechnology Bioengineering or a related field with 3 years of relevant experience
• M.S. with 2 years of relevant experience
• Equivalent combinations of education and experience will be considered

Experience & Skills

• Hands-on experience with mammalian cell culture and upstream bioprocessing
• Familiarity with single-use bioreactor systems and small-scale process development
• Experience designing and executing controlled experiments; DOE experience preferred
• Strong data analysis documentation and technical writing skills
• Working knowledge of GLP/GMP concepts and laboratory best practices
• Proficiency with standard data analysis and reporting tools (e.g. Excel PowerPoint)

Preferred Attributes

• Demonstrated ability to work independently in a fast-paced matrixed environment
• Strong problem-solving skills and attention to detail
• Ability to translate experimental data into practical insights
• Comfortable operating in environments with evolving requirements and priorities
• Collaborative mindset with a customer-centric orientation

Physical Requirements

• Ability to work in a laboratory environment and handle light to moderate lifting (up to 50 lbs)
• Standing and walking for extended periods during experimental execution
• Manual dexterity to operate laboratory equipment and instrumentation

Why Join the Bioprocess Design Center

The BDC is where Thermo Fisher technologies are stress-tested validated and transformed into real-world solutions for our customers. This role offers the opportunity to work hands-on with cutting-edge single-use systems contribute to evidence that shapes customer confidence and grow within a technically rigorous highly collaborative environment.

Compensation and Benefits

This position may also be eligible to receive a variable annual bonus based on company team and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on which includes:

• A choice of national medical and dental plans and a national vision plan including health incentive programs

• Employee assistance and family support programs including commuter benefits and tuition reimbursement

• At least 120 hours paid time off (PTO) 10 paid holidays annually paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave) accident and life insurance and short- and long-term disability in accordance with company policy

• Retirement and savings programs such as our competitive 401(k) U.S. retirement savings plan

• Employees Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

For more information on our benefits please visit: Experience:

IC