Senior Scientist- In Situ Biology
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Job Location:
Bothell, WA - USA
Monthly Salary:
$ 93600 - 151500
Posted on:
18 hours ago
Vacancies:
1 Vacancy
Job Summary
Why Patients Need You
Pfizers purpose is to deliver breakthroughs that change patients lives. Research and Development is at the heart of fulfilling Pfizers purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences ensuring drug safety and efficacy or supporting clinical trials you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.
POSITION SUMMARY
As a member of our ADC Discovery team you will perform spatial biology experiments to validate targets for antibody-based therapeutics as well as explore their effects on the tumor microenvironment. You will serve as a histopathology/immunohistochemistry subject matter expert representing the In Situ Biology sub-team and communicating findings to interdisciplinary project teams.
RESPONSIBILITIES
Independently design execute and interpret experiments aimed at understanding the spatial context of target expression in tumor and normal tissues.
Work with project teams management pathologists and peers within the Oncology Research Unit to ensure studies are aligned with project goals and best experimental practices.
Communicate with project teams to ensure executed studies satisfy intended goals and results are interpreted appropriately.
Present findings to project teams leadership and interdepartmental meetings.
Represent the In Situ Biology sub-team on project teams as a histopathology/immunohistochemistry subject matter expert and contribute to scientific discussions.
Evaluate propose and implement new procedures in step with advancing industry and academic standards.
Create reports contribute to internal and external presentations and journal articles and diligently record experiments in laboratory notebooks.
MINIMUM REQUIREMENTS Must Have
Recent PhD in a biological science related discipline OR
MS in a biological science related discipline with 7 years of experience with histopathology techniques OR
BS in a biological science related discipline with 9 years of experience with histopathology techniques.
IHC and ISH assay development expertise.
Experience with advanced histology methodologies including multiplex immunohistochemistry and in situ hybridization
An understanding of tumor biology.
Experience working collaboratively in a cross-functional research environment.
Experience handling multiple projects simultaneously.
Strong communication skillsverbal written and presentation.
Proficiency using laboratory notebooks and whole slide imaging using digital scanners.
Proficiency with Microsoft Office software including Excel and PowerPoint and analysis software like GraphPad Prism or Spotfire.
NICE TO HAVE
Experience with digital image analysis tools such as HALO and/or Visiopharm.
Experience with core histology methodologies such as processing embedding and sectioning.
Experience and interest in mentoring and leading colleagues.
PHYSICAL/MENTAL REQUIREMENTS
Lifting sitting standing walking bending ability to perform mathematical calculations and ability to perform complex data analysis.
NON-STANDARD WORK SCHEDULE TRAVEL OR ENVIRONMENT REQUIREMENTS
Occasional travel to other Pfizer sites for internal meetings or to external conferences.
Relocation support available
Work Location Assignment:On Premise
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care providers name address and the type of payments or other value received generally for public disclosure. Subject to further legal review and statutory or regulatory clarification which Pfizer intends to pursue reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse your name address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race color religion sex sexual orientation age gender identity or gender expression national origin disability or veteran status. Pfizer also complies with all applicable national state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing please email. This is to be used solely for accommodation requests with respect to the accessibility of our website online application process and/or interviewing. Requests for any other reason will not be returned.
Required Experience:
Senior IC
Key Skills
- Laboratory Experience
- Mammalian Cell Culture
- Biochemistry
- Assays
- Protein Purification
- Research Experience
- Next Generation Sequencing
- Research & Development
- cGMP
- Cell Culture
- Molecular Biology
- Flow Cytometry
About Company
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