Director, Product Management- Biopharma

Company Description

Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012 Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care including screening to find cancer early monitoring for recurrence in early-stage cancer and treatment selection for patients with advanced cancer. For more information visitand follow the company onLinkedInX (Twitter)andFacebook.

About the Product Department

Our Oncology Product team is responsible for the strategy and lifecycle management of our oncology portfolio and is comprised of two core areas:

• Assay Products: Liquid and tissue-based diagnostics for therapy selection and disease monitoring
• Digital Products: External-facing digital/data solutions and internal infrastructure supporting clinical and commercial operations

About the Role

The Director Product Management- Biopharma is a leadership position reporting to our Senior Director of Product Management. You would lead the strategy development and commercialization of Guardants biopharma-focused diagnostics portfolio ensuring our products are clinically impactful scientifically rigorous and aligned with the needs of our biopharma partners. Viable candidates will have deep expertise in oncology diagnostics and a passion for driving innovation at the intersection of medicine product strategy and biopharma collaboration. While not a requirement this is an ideal opportunity for clinically-trained MDs PhDs or MD/PhDs to work at the forefront of oncology diagnostics.

Key Responsibilities

Strategic Leadership & Portfolio Management

• Define and execute a comprehensive product strategy aligned with Guardants biopharma business objectives and oncology roadmap
• Lead cross-functional teams to design develop and deliver best-in-class assay and digital products for therapy selection and disease monitoring
• Translate market insights and partner needs into actionable product plans identifying unmet needs and prioritizing opportunities

Biopharma Engagement & Innovation

• Serve as the primary product liaison to the biopharma business unit ensuring alignment with biomarker-driven trials companion diagnostics and regulatory strategies
• Drive co-development partnerships and data generation initiatives to support product innovation and reimbursement
• Monitor emerging trends technologies and competitive activity to inform product differentiation and future roadmap

Clinical Integration & Commercialization

• Ensure products integrate seamlessly into oncology workflowsphysician nurse and patientto maximize adoption and usability
• Collaborate with Medical Affairs and Market Access to develop evidence strategies that demonstrate clinical utility and support payer engagement
• Oversee launch planning sales enablement and field training to ensure commercial readiness

Cross-Functional Collaboration

• Partner with R&D Clinical Development Regulatory and Commercial teams to drive execution across the product lifecycle
• Represent Guardant externally with oncologists healthcare systems payers and biopharma stakeholders to refine value propositions and identify unmet needs
• Contribute to publication planning clinical conference presentations and scientific communications

Qualifications

Required

• A Bachelors degree and 15 years of related experience or 10-12 years with a Masters degree; 8 years with a PhD; or 5 years with a PharmD/MD
• 8 years of experience in product management medical affairs or biopharma strategy within oncology diagnostics or precision medicine
• Proven success in launching and scaling diagnostic or healthcare products
• Strong understanding of liquid biopsy molecular diagnostics and biomarker-driven oncology

Preferred

• Masters and/or advanced scientific degree is highly preferred
• Experience in companion diagnostics biomarker development or clinical trial integration
• Familiarity with payer dynamics evidence generation and reimbursement strategies
• Exceptional communication analytical and leadership skills with the ability to influence across scientific clinical and commercial domains

Hybrid Work Model: This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays Tuesdays and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.