Senior Principal Scientist – Target Discovery & Biology (TD&B)

Career Category

Job Description

Join Amgens Mission of Serving Patients

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year. As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our award-winning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Senior Principal Scientist Target Discovery & Biology (TD&B)

What you will do

Lets do this. Lets change the world. Amgens Target Discovery & Biology (TD&B) organization integrates functional genomics screening multi-omics profiling human genetics and complex in vitro systems to uncover new biological insights and therapeutic targets. TD&B partners closely across Amgens therapeutic areas to translate data into discovery accelerating the path to target discovery and prosecution.

We are seeking a highly motivated innovative and experienced Senior Principal Scientist based in Thousand Oaks to lead a team focused on the development delivery and implementation of complex in vitro models that help power target discovery and functional genomics this essential role for discovery at Amgen you will be part of a dynamic cross-functional team to advance target and biological discovery across Amgens therapeutic this vital role you will:

• Provide scientific and operational leadership for a team of scientists delivering advanced in vitro models and screening-ready systems in collaboration with therapeutic area partners.
• Guide the design optimization and screen implementation of cellular models that capture disease-relevant biology integrating insights from disease tissue profiling data.
• Champion partnerships with automation colleagues accelerate model deployment and reproducibility.
• Collaborate with Amgen therapeutic area scientists to define requirements ensure biological relevance and deliver systems that enable mechanistic and translational insights.
• Identify and implement emerging technologies in cell engineering automation and complex model systems to enhance the sophistication and throughput of discovery platforms.
• Foster a collaborative creative and scientifically rigorous team culture committed to delivering impact across Amgens pipeline.

What we expect of you

We are all different yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.

Basic Qualifications:

Doctorate degree PhD OR PharmD OR MD and relevant post-doc where applicable and 3 years of directly related experience

Or

Masters degree and 6 years of directly related experience

Or

Bachelors degree and 8 years of directly related experience

Preferred Qualifications:

• Doctorate degree in cell biology molecular biology biomedical engineering or related discipline.
• 6 years of relevant experience in biotech or pharma including leadership of scientific teams.
• Strong track record in complex in vitro model development cell engineering and high-throughput or automated screening
• Experience with high-content imaging and transcriptional assay readouts
• Demonstrated ability to collaborate with cross-functional teams to translate disease biology into experimental models.
• Experience with viral vector systems (AAV lentivirus or related technologies) for gene delivery and perturbation.
• Experience in leading or mentoring scientists with proven success in project execution and team development.
• Familiarity with data-driven discovery approaches including integration of genetic or multi-omics insights.
• Excellent organizational and communication skills with the ability to drive cross-site collaboration in a matrixed research environment.

What you can expect of us

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture well support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to relevant skills experience and qualifications.

In addition to the base salary Amgen offers a Total Rewards Plan based on eligibility comprising of health and welfare plans for staff and eligible dependents financial plans with opportunities to save towards retirement or other goals work/life balance and career development opportunities that may include:

• A comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions group medical dental and vision coverage life and disability insurance and flexible spending accounts
• A discretionary annual bonus program or for field sales representatives a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.

Apply now and make a lasting impact with the Amgen team.

In any materials you submit you may redact or remove age-identifying information such as age date of birth or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Sponsorship

Sponsorship for this role is not guaranteed.

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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