Senior Principal AIML Engineer Research Sovereign AI

Position Summary

The Senior Principal AI/ML Engineer for AI Representation & EMR Vectorization is the senior technical leader and lead scientist responsible for architecting Mayo Clinics unified multimodal EMR representation layer. This role defines and builds the scientific substrate used by foundational models clinical agents and research applications. The individual serves as a hands-on expert and player-coach guiding technical strategy while contributing directly to model development graph construction and representation science. Over time this position will build and lead a specialized team.

Key Responsibilities

Scientific & Technical Leadership

• Design and implement Mayos multimodal EMR representation AI architecture including text imaging waveform structured data temporal sequences and multi-visit trajectories.
• Develop graph-based representations and knowledge graphs linking patients events attributes clinical concepts and embeddings.
• Integrate graph reasoning vector similarity search and hybrid vectorgraph pipelines for retrieval-augmented models and agentic reasoning.
• Define standards for temporal modeling drift-aware embeddings and sequence alignment across encounters.

Hands-On Modeling & Engineering

• Build large-scale embedding pipelines using transformer-based models contrastive learning graph neural networks and hybrid architectures.
• Implement efficient query layers using vector stores and graph databases.
• Develop interpretable embedding diagnostics attribution tools and graph-based audits to enable safe clinical use.
• Explore and implement methods for explaining similarity graph traversals temporal evolution and patient-neighborhood reasoning.

Cross-functional Collaboration

• Work with AI researchers on specialty-specific embeddings representation refinement and research prototypes.
• Collaborate with clinicians to operationalize clinically meaningful features phenotypes and longitudinal concepts.
• Provide scientific input to the Foundational Model Science Program to ensure alignment between representations and model architectures.

Team Leadership

• Serve as founding technical lead of the Reasoning EMR Representation team.
• Mentor junior scientists and engineers; build a future team specializing in representation learning and graph-based reasoning.

• Masters in Computer Science Machine Learning Biomedical Engineering or related field. 9 years of relevant experience or a bachelors degree with 11 years of relevant experience.
• Extensive (9 years) experience applying AI and machine learning in production healthcare environments or similar highly regulated or technology focused industries showcasing an acute understanding of healthcare technology.
• Hands-on expertise with graph databases and knowledge graph construction.
• Strong experience with transformer-based models contrastive learning and temporal modeling.

• Experience designing or deploying vector search systems and hybrid vectorgraph reasoning pipelines.

Preferred

• PhD or Masters in Computer Science Machine Learning Biomedical Engineering or related field.
• 10 years experience building production ML systems including multimodal architectures and representation learning.
• Experience with EMR data healthcare multimodality or clinical data integration.
• Experience building patient similarity models temporal embedding systems or phenotype discovery pipelines.
• Strong background in explainability causality or interpretable ML.
• Prior experience in a playercoach or team-lead role.