Principal Research Associate, Bioanalytical
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Job Location:
Boston, NH - USA
Monthly Salary:
$ 86500 - 129800
Posted on:
11 hours ago
Vacancies:
1 Vacancy
Job Summary
Job Description
Employer: Vertex Pharmaceuticals Incorporated
JOB TITLE: Principal Research Associate Bioanalytical
LOCATION: 316-318 Northern Ave Boston Massachusetts 02210
OPENINGS: 1
DUTIES:
- Conduct bioanalytical assays to support preclinical study sample analysis.
- Carry out method development and optimization to quantify target proteins.
- Maintain proper documentation of experiments and support QC data review.
- Collaborate with cross-functional teams to review study design and interpret results.
- Prepare technical reports and presentations to document and communicate results.
REQUIREMENTS: Employer will accept a Masters degree or equivalent in applied science biotechnology or a related field and 3 years of experience in the job offered or in a Principal Research Associate Bioanalytical-related occupation.
Position requires demonstrable experience in the following:
Perform biochemical and ligand binding assays to support sample analysis from preclinical studies including protein extraction and quantification automated capillary western blot ELISA MSD and ELISPOT. Drive splenocyte isolation and cell culture. Coordinate sample storage data analysis and interpretation using GraphPad PRISM. Perform assay development optimization and qualification according to FDA guidelines for bioanalytical method validation. Execute and document assays ELN with good laboratory practices and good documentation practices. Coordinate biodistribution toxicology and pharmacology studies for investigational new drug application. Conduct biochemistry and molecular biology on CRISPR strategies for gene and cell therapies. Perform statistical analysis including 4PL regression analysis standard deviation and coefficients of variation calculations.
Rate of Pay: $86500.00 - $129800.00
CONTACT: Send Resume to . Reference 12140.705. EOE.
Pay Range:
$0 - $0Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors including skills competencies experience and other job-related factors permitted by law.
At Vertex our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career financial family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter) educational assistance programs including student loan repayment a generous commuting subsidy matching charitable donations 401(k) and so much more.
Flex Designation:
On-Site DesignatedFlex Eligibility Status:
In this On-Site designated role you will work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.
#LI-Onsite
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at
Required Experience:
Staff IC
Key Skills
- Laboratory Experience
- ELISA
- Immunoassays
- Mammalian Cell Culture
- Biochemistry
- Cell Biology
- Research Experience
- Cell Culture
- Molecular Biology
- Microscopy
- Research Laboratory Experience
- Western Blot
About Company
Vertex Pharmaceuticals invests in scientific innovation to create transformative medicines for people with serious diseases.
