Senior Scientist, Assay Development

At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at

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About Innovative Medicine:

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

Learn more at are searching for the best talent for a Senior Scientist Assay Development to be onsite in Cambridge MA.

Purpose:
The in Vivo Antibody Discovery group within Biologics Discovery is responsible for lead antibody generation from immunized animals with state-of-the-art technologies including single B cell sorting hybridoma display and microfluidics. As a member of the IVAD Group this role will be responsible for the development and implementation of biochemical or cell-based binding and functional assays to support antibody generation against targets in different disease areas. In-depth knowledge and hands-on experience in assay development on Beacon microfluidics will be preferred. A strong understanding of cell biology and disease molecular pathways will also be important. This is a critical function in a multifaceted Biologics Discovery organization committed to bringing the next generation of biotherapeutic molecules to patients. We are looking for a motivated candidate with scientific and technical expertise who can collaborate across discovery areas to bring value to our portfolio of innovative drug concepts. Proficiency to work within a highly coordinated fast-paced environment will be a significant attribute. An additional knowledge base in the areas of oncology immunology infectious disease or cardiovascular disease would be a plus. If this sounds like you come join our team!

You will be responsible for:

• Design and optimize biochemical/cell-based binding and functional assays with appropriate reagents for antibody screening
• Execute antibody discovery workflow on Beacon microfluidics platform to screen for functional antibody hits
• Evaluate animal serology using appropriate assays to select animals for screening
• Present research findings in internal meetings clearly communicating scientific results and providing insights into data interpretation.
• Collaborate with multidisciplinary teams across functional areas to advance therapeutic programs in a dynamic and fast-paced environment.
• Document work accurately and promptly using Electronic Lab Notebook systems (e.g. Signal) and create detailed SOPs.

Qualifications / Requirements:

Education and Years of Experience:

• Minimum of a Bachelors degree is required
• PhD in Molecular Biology Biomedical Engineering Biochemistry or a related field is highly preferred

Required:

• Minimum 4 years of experience in the pharmaceutical industry and/or academic setting
• Hands-on experience in assay development with expertise on protein-based binding assays and cell-based binding and functional assays
• In-depth knowledge on mAb bi-specifics and multi-specifics as therapeutics
• Working knowledge on microfluidics-based antibody discovery platform (ideally Beacon)

Preferred:

• Assay development experience on microfluidics-based antibody discovery platform
• Flow cytometry expertise for single B cell sorting
• Experience or knowledge on generation of right reagents/cell lines for assay development on Beacon platform

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation external applicants please contact us via internal employees contact AskGS to be directed to your accommodation resource.

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Senior IC