Accounts Payable Manager

Madrigal is a biopharmaceutical company focused on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) a serious liver disease that can progress to cirrhosis liver failure need for liver transplantation and premature mortality. Every member of our Madrigal team is connected by our shared purpose: leading the fight against MASH.

Madrigals medication Rezdiffra (resmetirom) is a once-daily oral liver-directed THR-β agonist designed to target key underlying causes of MASH. Rezdiffra is the first and only medication approved by both the FDA and European Commission for the treatment of MASH with moderate to advanced fibrosis (F2 to F3). An ongoing Phase 3 outcomes trial is evaluating Rezdiffra for the treatment of compensated MASH cirrhosis (F4c).

Our success is driven by our people. We are building a dynamic inclusive and high-performing culture that values scientific excellence operational rigor and collaboration. To support our continued growth we are strengthening our workforce strategy to ensure we have the right talent at the right time in the right way.

Position Overview:

We are seeking an initiative-taking Accounts Payable Manager to own the complete invoice-to-payment cycle across several European countries with growth expected.

This position reports to the Director of Accounting International and requires both operational excellence and strategic thinking. You will take our Coupa platform from basic implementation to full utilization by building the reporting infrastructure automation capabilities and cross-functional partnerships needed to support our expansion.

The role demands someone who can bring structure and discipline to build out the AP function. Immediate priorities include driving vendor adoption of automation tools maintaining current invoice processing without backlogs and establishing comprehensive AP metrics. The ideal candidate thrives on implementing improvements and operating independently while collaborating across functions.

Core Responsibilities

Process Ownership & Execution

• Own the accounts payable process from invoice receipt through payment execution and month-end reconciliation across multiple European entities.
• Process invoices through Coupa with accuracy and efficiency ensuring data completeness and policy compliance.
• Execute weekly payment runs ensuring approval compliance vendor term adherence and alignment with cash flow requirements.
• Manage specialized payment streams including travel expenses car leases and Health Care Professional engagements.
• Monitor and administer manual out-of-scope payments when required.

Vendor Management & Automation

• Serve as the primary contact for vendor and business inquiries regarding invoices payment status and issue resolution.
• Drive vendor adoption of Coupas supplier portal and electronic invoicing capabilities to maximize automation and minimize manual processing.
• Partner with Procurement to strengthen vendor onboarding processes and ensure upstream requisitioning practices support efficient AP operations.

Data Integrity & Month-End Close

• Ensure the AP subledger remains accurate complete and continuously reconciled with proactive resolution of discrepancies before close deadlines.
• Partner with FP&A on accrual schedules then proactively pursue outstanding invoices to reduce accrual levels and improve close accuracy.
• Track vendor invoicing patterns and flag systemic delays that impact financial reporting.
• Support internal statutory and tax audits with timely documentation and reconciliations.

Reporting Analytics & Continuous Improvement

• Build a comprehensive AP reporting framework - establishing metrics including vendor portal adoption rates invoice volumes automation levels and processing efficiency.
• Develop and monitor KPIs such as invoice cycle times payment timeliness exception rates PO compliance percentages aging trends and automation performance.
• Provide accurate payment forecasts to support treasury cash flow planning.
• Identify and implement process improvements that reduce manual work strengthen controls and build scalable processes.

Cross-Functional Collaboration

• Work with Procurement to reinforce PO compliance and ensure requisitioning processes support AP efficiency.
• Collaborate with Treasury on funding requirements and payment releases.
• Leverage FP&A accrual information to drive timelier invoice receipt and processing.
• Partner with Legal Procurement and Finance teams to support end-to-end process alignment.

Qualifications and Skills Required:

• Bachelors degree in Accounting Finance or related field
• Minimum 10 years of accounts payable experience ideally in multinational or high-growth environments
• Thrives in fast-evolving environments and brings structure and discipline to AP processes
• Demonstrated ability to learn and optimize AP systems quickly - you do not need to be a Coupa expert coming in but you must be eager to master it
• Experience working across multiple finance systems; comfort with technology and ability to adapt to new tools
• Understanding of VAT/tax requirements across European jurisdictions
• Strong Excel/Power BI skills to build trackers reconciliations and analytical frameworks
• Ability to work independently while managing multiple priorities across entities
• Strong organizational skills diligence and accountability
• Strong interpersonal and communication skills; ability to influence stakeholders without direct authority

All full-time employees receive equity which reinforces our ownership culture and offers meaningful opportunity for our employees to share in the success they help create. By aligning individual and company performance we empower employees to think like owners giving them a stake in the organization.

Full-time employees are also eligible for comprehensive benefits including flexible paid time off medical dental vision and life/disability insurance and 401(k) offerings (i.e. traditional Roth and employer match) in accordance with applicable plans. We also offer additional voluntary benefits like supplemental life insurance legal services and other addition we offer mental health benefits through our Employee Assistance Program for employees and their family. The company also provides other benefits in accordance with applicable federal state and local laws.

We are committed to providing reasonable accommodations for individuals with disabilities throughout the hiring process. If you need assistance please contact

Madrigal is an Equal Opportunity Employer. All employment is decided on the basis of qualifications merit and business need. Applicants will receive consideration for employment without regard to race ethnicity color religion sex gender identity sexual orientation national origin age disability protected veteran or disabled status or other characteristic protected by applicable federal state or local law.

Unsolicited resumes from agencies should not be forwarded to Madrigal. Madrigal will not be responsible for any fees arising from the use of resumes through this source. Madrigal will only pay a fee to agencies if a formal agreement between Madrigal and the agency has been established.

Applications are being accepted on an ongoing basis and can be submitted through our Madrigal Careers site.

Please be aware that we have received reports of individuals misrepresenting themselves as Madrigal Pharmaceuticals Hiring Managers seeking to engage with job candidates through fraudulent online advertisements or job posting sites. These unauthorized individuals are using Madrigals name and logo in an attempt to solicit up-front fees and obtain personal information from interested job candidates. Please know that Madrigal does not conduct interviews via text or in chat rooms; conduct interviews via Skype RingCentral or solely via telephone; charge candidates an advance fee of any kind (e.g. fees for purchasing equipment); nor does it offer positions of employment without undergoing a thorough recruiting process.

Please also note that any correspondence with regard to employment would come from an authorized email address or from an email address from one of our trusted search firm partners. We are aware that incorrect/fraudulent email addresses with Madrigal misspelled have been utilized in these most recent fraud attempts. If you receive unsolicited employment offers from people claiming to work for or on behalf of Madrigal we recommend that you: do not respond to their questions; do not open any attachments; and do not click on any hyperlinks. Any questions regarding the legitimacy of job-related contacts can be directed to .