We are seeking a highly motivated Associate Scientist with expertise in CRISPR gene editing and iPSC engineering to join our diabetes research team. This lab-based role will focus on advancing stem cell engineering and developing next-generation islet cell therapies. The ideal candidate will have hands-on experience in gene editing molecular biology and human iPSC culture and differentiation.
Key Responsibilities
- Perform CRISPR-based gene editing and optimize workflows for gRNA screening and delivery.
- Develop and characterize clonal gene-edited iPSC lines using flow cytometry ddPCR dPCR and qPCR.
- Maintain routine iPSC culture passaging and media preparation.
- Execute directed differentiation of human iPSCs to pancreatic islets and assess drug substance quality (cell counts viability metabolite analysis).
- Conduct on-/off-target analysis via PCR and NGS workflows.
- Collaborate cross-functionally to support assay transfer from R&D to GMP environments.
- Maintain accurate experimental records prepare reports and contribute to SOP development.
Qualifications :
Required:
- B.S. in Stem Cell Biology Cell Biology Bioengineering or related field with 34 years of relevant industry experience; OR M.S. with 12 years experience.
- Hands-on experience with human iPSC culture and CRISPR gene editing.
- Proficiency in molecular biology techniques (PCR ddPCR dPCR NGS).
- Familiarity with flow-based sorting and assay development (ELISA luciferase assays).
- Strong organizational and communication skills.
Preferred:
- Experience in pancreatic islet differentiation and transitioning processes to GMP.
- Familiarity with electronic lab notebooks (ELN).
- Authorization to work in the United States indefinitely without restriction or sponsorship.
Additional Information :
The position is Full Time Monday-Friday 8am-5pm with occasional weekends (on a rotational basis to support cell culture). Candidates currently living within a commutable distance of Boston MA are encouraged to apply.
What to Expect in the Hiring Process:
- 10-15 Minute Phone Interview with Region Recruiter
- 45-60 Minute Virtual Interview with Manager and/or Group Leader
- 45-60 Minute In-Person Meeting over Coffee for a Casual Discussion of the Role
What We Offer:
- Target pay range: $37-41/hr
- Excellent full-time benefits including comprehensive medical coverage dental and vision options
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
- Yearly goal-based bonus & eligibility for merit-based increases
Ready to make an impact in cutting-edge cell therapy
Apply today and join Eurofins PSS in advancing CRISPR gene editing and iPSC engineering for next-generation diabetes treatments.
Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.
Remote Work :
No
Employment Type :
Full-time
We are seeking a highly motivated Associate Scientist with expertise in CRISPR gene editing and iPSC engineering to join our diabetes research team. This lab-based role will focus on advancing stem cell engineering and developing next-generation islet cell therapies. The ideal candidate will have ha...
We are seeking a highly motivated Associate Scientist with expertise in CRISPR gene editing and iPSC engineering to join our diabetes research team. This lab-based role will focus on advancing stem cell engineering and developing next-generation islet cell therapies. The ideal candidate will have hands-on experience in gene editing molecular biology and human iPSC culture and differentiation.
Key Responsibilities
- Perform CRISPR-based gene editing and optimize workflows for gRNA screening and delivery.
- Develop and characterize clonal gene-edited iPSC lines using flow cytometry ddPCR dPCR and qPCR.
- Maintain routine iPSC culture passaging and media preparation.
- Execute directed differentiation of human iPSCs to pancreatic islets and assess drug substance quality (cell counts viability metabolite analysis).
- Conduct on-/off-target analysis via PCR and NGS workflows.
- Collaborate cross-functionally to support assay transfer from R&D to GMP environments.
- Maintain accurate experimental records prepare reports and contribute to SOP development.
Qualifications :
Required:
- B.S. in Stem Cell Biology Cell Biology Bioengineering or related field with 34 years of relevant industry experience; OR M.S. with 12 years experience.
- Hands-on experience with human iPSC culture and CRISPR gene editing.
- Proficiency in molecular biology techniques (PCR ddPCR dPCR NGS).
- Familiarity with flow-based sorting and assay development (ELISA luciferase assays).
- Strong organizational and communication skills.
Preferred:
- Experience in pancreatic islet differentiation and transitioning processes to GMP.
- Familiarity with electronic lab notebooks (ELN).
- Authorization to work in the United States indefinitely without restriction or sponsorship.
Additional Information :
The position is Full Time Monday-Friday 8am-5pm with occasional weekends (on a rotational basis to support cell culture). Candidates currently living within a commutable distance of Boston MA are encouraged to apply.
What to Expect in the Hiring Process:
- 10-15 Minute Phone Interview with Region Recruiter
- 45-60 Minute Virtual Interview with Manager and/or Group Leader
- 45-60 Minute In-Person Meeting over Coffee for a Casual Discussion of the Role
What We Offer:
- Target pay range: $37-41/hr
- Excellent full-time benefits including comprehensive medical coverage dental and vision options
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
- Yearly goal-based bonus & eligibility for merit-based increases
Ready to make an impact in cutting-edge cell therapy
Apply today and join Eurofins PSS in advancing CRISPR gene editing and iPSC engineering for next-generation diabetes treatments.
Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.
Remote Work :
No
Employment Type :
Full-time
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