Downstream Process Development Engineer, Bioproduction (Plainville, MA)

Work Schedule

Environmental Conditions

Job Description

This Scientist leads downstream process development and technology enablement using Thermo Fishers single-use purification platforms. This role advances our mission of evidence generation customer training and process innovation working to accelerate customer adoption and operational excellence.

Acting as a technical liaison for customers R&D and manufacturing this position develops scalable data-driven purification strategies for recombinant proteins and novel modalities. This role drives internal capability-building through structured training workshops and mentorship ensuring Thermo Fisher teams and customers alike can expertly implement guidelines in single-use chromatography and filtration systems.

Location:

This is an onsite position in Plainville Massachusetts. Residency within commuting distance is required. No relocation assistance will be provided.

Key Responsibilities

Customer Process Development and Evidence Generation

Design and implement purification process development studies across capture intermediate and polishing operations.
Generate high-quality datasets demonstrating system performance reproducibility and scalability across Thermo Fishers downstream single-use platforms (e.g. Dyna Chrom Dyna Spin). Develop and publish robust technical data packages supporting customer confidence and commercial product claims.
Collaborate with global R&D and product management teams to translate customer use cases into platform enhancements and application notes.

Customer Engagement and Training

Lead hands-on customer training and technology demonstrations focused on chromatography filtration and process analytics.
Deliver engaging training that accelerates adoption of Thermo Fishers purification technologies.
Partner with field and commercial teams to implement customer workshops and data-driven showcases that highlight process performance and reliability.

Internal Enablement and Capability Building

Conduct structured internal workshops and technical upskilling sessions to embed downstream process knowledge within Thermo Fisher teams.
Mentor emerging scientists and engineers in purification process design experimental planning and data analysis.
Codify downstream guidelines and lessons learned into SOPs templates and internal knowledge libraries.

Technology Innovation and Collaboration

Partner with upstream automation and analytical colleagues to integrate end-to-end single-use workflows within the BDC.
Contribute to continuous improvement of purification process automation data acquisition and control systems.
Find opportunities to standardize downstream workflows across customer applications to improve scalability reproducibility and time-to-validation.

Education and Experience

B.S in Chemical Engineering Biochemistry Biotechnology or related field with 5 years of meaningful experience; M.S. with 3 years; or PhD
Proven experience developing optimizing and transferring recombinant protein purification processes (chromatography UF/DF process characterization).
Demonstrated proficiency in downstream single-use system implementation and process solving.
Familiarity with data capture process automation and integration of analytics for process insight.

Competencies

Advanced knowledge of downstream bioprocess operations and system integration.
Demonstrated ability to generate technical evidence supporting process robustness and product claims.
Skilled communicator with experience delivering customer trainings and technical presentations.
Ability to design and complete sophisticated experimental plans aligned with measurable metrics.
Strong collaboration skills and comfort operating within a global matrixed organization.

Compensation and Benefits

This position may also be eligible to receive a variable annual bonus based on company team and/or individual performance results in accordance with company policy. We offer a comprehensive Total Rewards package that our U.S. colleagues and their families can count on which includes:

• A choice of national medical and dental plans and a national vision plan including health incentive programs

• Employee assistance and family support programs including commuter benefits and tuition reimbursement

• At least 120 hours paid time off (PTO) 10 paid holidays annually paid parental leave (3 weeks for bonding and 8 weeks for caregiver leave) accident and life insurance and short- and long-term disability in accordance with company policy

• Retirement and savings programs such as our competitive 401(k) U.S. retirement savings plan

• Employees Stock Purchase Plan (ESPP) offers eligible colleagues the opportunity to purchase company stock at a discount

For more information on our benefits please visit: