Scientist iPSC Gene Editing
Share
Job Location:
Boston, NH - USA
Monthly Salary:
Not Disclosed
Posted on:
8 hours ago
Vacancies:
1 Vacancy
Job Summary
We are seeking a highly skilled passionate and motivated scientist to join our Bioproduct Research and Development team. This position will play a key lab-based role in iPSC gene editing and will contribute to the development of next-generation islet cell therapies. Ideal candidates will have extensive hands-on experience with human iPSC culture CRISPR-based gene editing molecular biology and assay development.
The successful candidate will be responsible for daily R&D and GMP gene-editing operations including iPSC culture gene editing platform development and optimization documentation preparation (SOP and batch record drafting and review) deviation investigation raw material screening clone characterization and as well small-scale iPSC derived islet differentiation.
Key Responsibilities:
- Lab-based role focused on advancing CRISPR-based iPSC gene editing and iPSC cell line generation to enable GMP readiness.
- Develop and optimize gene-editing workflows including gRNA design RNP delivery knock-in cargo design clone genetic screening and cell banking.
- Characterize edited iPSC clones using DNA-based assays (PCR qPCR ddPCR) sequencing flow cytometry and next-generation sequencing (NGS).
- Evaluate and implement iPSC culture media optimization and gene editing strategies to ensure genomic stability of iPSC lines.
- Support and refine directed differentiation of iPSCs into islet cells and characterize resulting drug product attributes.
- Perform hands-on iPSC gene editing within GMP settings to generate clinical-grade cell lines.
- Draft review and execute SOPs and master batch records; ensure compliance with GMP regulatory and quality standards; support deviation investigations and maintain thorough documentation.
- Participate in supplier qualification and sourcing of critical raw materials and consumables to ensure GMP readiness.
- Demonstrate strong teamwork communication and organizational skills to manage multiple projects and timelines effectively.
Qualifications :
Minimum Required Qualifications:
- Ph.D. in biology bioengineering or a related field with 0-1 years of relevant industry experience in iPSC gene editing and cell therapy.
- Extensive experience with human iPSC culture gene editing and molecular biology techniques.
- Proficiency in CRISPR gene editing including optimization of protocols
- Proficiency in gene editing workflows and molecular biology techniques including construct design cell delivery methods PCR ddPCR flow cytometry and NGS.
- Ability to troubleshoot and interpret experimental results and effectively present conclusions.
- Excellent communication and interpersonal skills with the ability to work effectively in a team-oriented environment.
- Strong organizational skills and diligent record keeping.
Preferred Qualifications:
- Hands-on GMP gene editing operational experience.
- Experience in direct differentiation and scale-up of iPSC-derived cells.
- Familiarity with electronic lab notebook (ELN) documentation.
- Authorization to work in the United States indefinitely without restriction or sponsorship.
Additional Information :
What to Expect in the Hiring Process:
- 10-15 Minute Phone Interview with Region Recruiter
- 45-60 Minute Virtual Interview with Manager and/or Group Leader
- 45-60 Minute In-Person Meeting over Coffee for a Casual Discussion of the Role
The Position is full-time Monday through Friday 8am-5pm with occasional weekends (on a rotational basis to support cell culture). Candidates currently living within a commutable distance of Boston MA are encouraged to apply.
What We Offer:
- Excellent full-time benefits including comprehensive medical coverage dental and vision options
- Life and disability insurance
- 401(k) with company match
- Paid vacation and holidays
- Yearly goal-based bonus & eligibility for merit-based increases
- Compensation is anually
Ready to make an impact
Join a team where your scientific skills matter and your growth is supported. If youre passionate about quality collaboration and continuous improvement we want to hear from you. Apply today and take the next step in your career with Eurofins PSS!
Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.
Remote Work :
No
Employment Type :
Full-time
Key Skills
- Laboratory Experience
- Immunoassays
- Machine Learning
- Biochemistry
- Assays
- Research Experience
- Spectroscopy
- Research & Development
- cGMP
- Cell Culture
- Molecular Biology
- Data Analysis Skills
About Company
Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and the environment safer, healthier and more sustainable. From the food you eat to the medicines you rely on, Eur ... View more
