Associate Scientist In Vivo Pharmacology
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Job Location:
San Diego, CA - USA
Monthly Salary:
Not Disclosed
Posted on:
Yesterday
Vacancies:
1 Vacancy
Job Summary
Working with Us
Challenging. Meaningful. Life-changing. Those arent words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here uniquely interesting work happens every day in every department. From optimizing a production line to the latest breakthroughs in cell therapy this is work that transforms the lives of patients and the careers of those who do it. Youll get the chance to grow and thrive through opportunities uncommon in scale and scope alongside high-achieving teams. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits services and programs that provide our employees with the resources to pursue their goals both at work and in their personal lives. Read more: Protein Homeostasis Thematic Research Center (TRC) at BMS is a fundamental Oncology research engine delivering oncology and hematology therapeutics to patients. The TRC has a major focus on exploiting BMS expertise in protein degradation to discover and develop therapies aimed at tumor intrinsic vulnerabilities and mechanisms of resistance to existing cancer therapeutics. This focus on protein degradation allows us to attack protein classes that were previously deemed undruggable.
The Pharmacology group within the Protein Homeostasis TRC at BMS San Diego provides in vivo pharmacology support to discovery teams focused on developing small molecules and biologics for oncology and immune-oncology. As an integral part of discovery programs the group supports lead identification through in vivo model screening and mechanism-of-action studies develops and validates animal disease models identifies pathway biomarkers and establishes clinically relevant endpoints to assess efficacy. Collaboration with DMPK Exploratory Toxicology and Translational Development is central to our work and we contribute preclinical data to inform clinical development plans.
Position Summary:
We are seeking a motivated Associate Scientist with broad experience in pharmacology and drug discovery for both small and large molecules. The successful candidate will work collaboratively in a multidisciplinary environment taking responsibility for experiment design planning and execution. Key duties include interpreting and presenting in vivo data conducting sample and endpoint analyses (ELISA Western blot Jess qPCR IHC) and preparing protocols and reports. The role requires independent work technical expertise and contributions to project decisions. Strong communication self-motivation innovation flexibility and teamwork are essential.
Position Responsibilities:
In the role as an Associate Scientist within Pharmacology the ideal candidate will be responsible for the following:
Develop disease models for oncology and immune-oncology
Independently design and execute in vivo efficacy and PK/PD experiments to identify drug candidates
Analyze and interpret data accurately reporting findings to supervisors and colleagues
Troubleshoot routine issues and recommend solutions
Evaluate endpoints from in vivo studies using Western blots mesoscale qPCR etc.
Write precise protocols and technical reports
Present data to multidisciplinary discovery teams
Collaborate with cross-functional team members
Basic Qualifications:
Bachelors Degree
2 years of academic and / or industry experience
Preferred Qualifications:
Bachelors Degree and 2 years of academic and / or industry experience with oncology models
Experience in mammalian cell culture
Experience in the development of syngeneic and xenograft cancer models
Proficient in animal handling dosing (PO IP IV and SC) tumor cell inoculation data collection and analysis
Hands-on experience in small animal surgeries necropsy and tissue and blood collection
Hands-on experience in evaluating small molecules in animal models
Experience with small animal imaging modalities (e.g. Xenogen ultrasound etc.) is a plus.
Skilled in Western blots ELISA MesoScale IHC flow cytometry RNA/DNA extraction and PCR
Proficient in Excel Word PowerPoint FlowJo GraphPad Prism and Studylog
Excellent interpersonal communication presentation collaboration and organizational skills
Detail-oriented focused and able to deliver high-quality data efficiently
LI-Onsite
If you come across a role that intrigues you but doesnt perfectly line up with your resume we encourage you to apply anyway. You could be one step away from work that will transform your life and career.
Compensation Overview:
The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job such as required skills where the job is performed the employees work schedule job-related knowledge and experience. Final individual compensation will be decided based on demonstrated experience.
Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits please visit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical pharmacy dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability life insurance supplemental health insurance business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays Global Shutdown Days between Christmas and New Years holiday up to 120 hours of paid vacation up to two (2) paid days to volunteer sick time off and summer hours flexibility. Parental caregiver bereavement and military leave. Family care services such as adoption and surrogacy reimbursement fertility/infertility benefits support for traveling mothers and child elder and pet care resources. Other perks like tuition reimbursement and a recognition program.
Uniquely Interesting Work Life-changing Careers
With a single vision as inspiring as Transforming patients lives through science every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture promoting global participation in clinical trials while our shared values of passion innovation urgency accountability inclusion and integrity bring out the highest potential of each of our colleagues.
On-site Protocol
BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential site-by-design field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role:
Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles onsite presence is considered an essential job function and is critical to collaboration innovation productivity and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.
Supporting People with Disabilities
BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application or in any part of the recruitment process direct your inquiries to . Visit to access our complete Equal Employment Opportunity statement.
Candidate Rights
BMS will consider for employment qualified applicants with arrest and conviction records pursuant to applicable laws in your area.
If you live in or expect to work from Los Angeles County if hired for this position please visit this page for important additional information: Protection
We will never request payments financial information or social security numbers during our application or recruitment process. Learn more about protecting yourself at data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.
Key Skills
- Laboratory Experience
- ELISA
- Immunoassays
- Transfection
- Mammalian Cell Culture
- Suspension Experience
- Biochemistry
- Assays
- cGMP
- Cell Culture
- Molecular Biology
- Flow Cytometry
About Company
Bristol-Myers Squibb is a global biopharmaceutical company focused on discovering, developing and delivering innovative medicines for patients with serious diseases. Our medicines are helping millions of patients around the world in disease areas such as oncology, cardiovascular, immu ... View more
