Senior Scientist I II, Drug Delivery Modeling & Simulation

Irvine, CA - USA

Monthly Salary: Not Disclosed

Posted on: 3 hours ago

Vacancies: 1 Vacancy

Job Summary

As Senior Scientist I or II in AbbVie Drug Delivery Sciences you will work as a key part of a talented multidisciplinary and cross-functional team to build cutting-edge capabilities for the delivery of biologics and small molecules and advance new products through early R&D. We are seeking a highly motivated PhD Chemical Engineer specializing in the modeling and simulation of drug release kinetics in advanced drug delivery systems. The successful candidate will apply first-principles understanding to design optimize and analyze drug delivery platforms utilizing quantitative models to predict and control drug release profiles.

Responsibilities:

Develop and apply mechanistic models for drug release kinetics from various sustained drug delivery platforms (e.g. in situ forming depots implants hydrogels etc.).
Employ first-principles approaches (e.g. diffusion convection chemical reaction theories) to solve complex transport problems relevant to drug delivery formulations.
Design execute and analyze computational simulations using tools such as COMSOL Multiphysics or similar platforms.
Collaborate with formulation and material scientists and pharmacologists to translate modeling results into experimental design and product development.
Interpret experimental release data and integrate findings into enhanced models for predictive accuracy.
Communicate findings through technical reports publications and presentations

Qualifications :

PhD in Chemical Engineering
Senior Scientist I: PhD with 0 - 4 years of relevant experience (industry post-docs or academia).
Senior Scientist II: PhD with 4 years of relevant industry experience.
Strong foundation in mass transport phenomena (diffusion dissolution convection degradation).
Demonstrated expertise in mathematical modeling and simulation of controlled release mechanisms.
Proficiency in relevant modeling and simulation software (COMSOL Multiphysics Monte Carlo methods or equivalent)
Excellent problem-solving quantitative and communication skills.
Ability to work collaboratively in a multidisciplinary environment.
Prior experience with drug delivery system design and evaluation is preferred.

Leadership Competencies:

Deals comfortably with risk and ambiguity changing course when needed.
Lives AbbVie values. Acts consistently with our ethics obligations and the law.
Acts respectfully yet courageously.
Communicates openly and honestly with all colleagues.
Look outside AbbVie for new ideas to stimulate innovation.
Connects unrelated concepts generates original or unique ideas.
Persistent and resilient - finds the way to move good ideas forward.

Additional Information :

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

This is an on-site opportunity located in AbbVies Irvine CA location.
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
This job is eligible to participate in our long-term incentive programs

Note: No amount of pay is considered to be wages or compensation until such amount is earned vested and determinable. The amount and availability of any bonus commission incentive benefits or any other form of compensation and benefits that are allocable to a particular employee remains in the Companys sole and absolute discretion unless and until paid and may be modified at the Companys sole and absolute discretion consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more visit & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:

Work :

Employment Type :

Full-time

Responsibilities:

Develop and apply mechanistic models for drug release kinetics from various sustained drug delivery platforms (e.g. in situ forming depots implants hydrogels etc.).
Employ first-principles approaches (e.g. diffusion convection chemical reaction theories) to solve complex transport problems relevant to drug delivery formulations.
Design execute and analyze computational simulations using tools such as COMSOL Multiphysics or similar platforms.
Collaborate with formulation and material scientists and pharmacologists to translate modeling results into experimental design and product development.
Interpret experimental release data and integrate findings into enhanced models for predictive accuracy.
Communicate findings through technical reports publications and presentations

Qualifications :

PhD in Chemical Engineering
Senior Scientist I: PhD with 0 - 4 years of relevant experience (industry post-docs or academia).
Senior Scientist II: PhD with 4 years of relevant industry experience.
Strong foundation in mass transport phenomena (diffusion dissolution convection degradation).
Demonstrated expertise in mathematical modeling and simulation of controlled release mechanisms.
Proficiency in relevant modeling and simulation software (COMSOL Multiphysics Monte Carlo methods or equivalent)
Excellent problem-solving quantitative and communication skills.
Ability to work collaboratively in a multidisciplinary environment.
Prior experience with drug delivery system design and evaluation is preferred.

Leadership Competencies:

Deals comfortably with risk and ambiguity changing course when needed.
Lives AbbVie values. Acts consistently with our ethics obligations and the law.
Acts respectfully yet courageously.
Communicates openly and honestly with all colleagues.
Look outside AbbVie for new ideas to stimulate innovation.
Connects unrelated concepts generates original or unique ideas.
Persistent and resilient - finds the way to move good ideas forward.

Additional Information :

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

This is an on-site opportunity located in AbbVies Irvine CA location.
The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location and we may ultimately pay more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation holidays sick) medical/dental/vision insurance and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
This job is eligible to participate in our long-term incentive programs

AbbVie is an equal opportunity employer and is committed to operating with integrity driving innovation transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more visit & Puerto Rico applicants seeking a reasonable accommodation click here to learn more:

Work :

Employment Type :

Full-time

Key Skills

Laboratory Experience
Mammalian Cell Culture
Biochemistry
Assays
Protein Purification
Research Experience
Next Generation Sequencing
Research & Development
cGMP
Cell Culture
Molecular Biology
Flow Cytometry

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About Company

AbbVie

AbbVie is a global biopharmaceutical company focused on creating medicines and solutions that put impact first for patients, communities, and our world. We aim to address complex health issues and enhance people's lives through our core therapeutic areas: immunology, oncology, neuro ... View more

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