Postdoctoral Associate
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Job Location:
Houston, MS - USA
Monthly Salary:
Not Disclosed
Posted on:
12 hours ago
Vacancies:
1 Vacancy
Job Summary
Title:Postdoctoral Associate
Division:Pediatrics ()
Department:Pediatrics - Oncology AICT ()
Location: Houston (1100)
Salary Range:$64356
Work Schedule:Monday Friday 8 a.m. 5 p.m.
Employment Duration:Full-time
FLSA Status:Exempt
Summary
We seek a highly motivated postdoctoral fellow to lead a translational immunotherapy project focused on advancing next-generation CAR T-cell therapies for pediatric solid tumors. The fellow will apply high-throughput screening T-cell engineering and single-cell analytics to identify and validate novel receptor designs that enhance anti-tumor activity. This role offers the opportunity to drive impactful preclinical research in a collaborative multidisciplinary environment. Ideal candidates will have experience in cellular immunotherapy molecular cloning and data analysis with a strong interest in developing innovative cancer treatments.
Job Duties
- Designs and executes experiments involving CAR T-cell engineering transduction and functional assays as well as barcoded DNA libraries.
- Analyzes pooled barcoded screens and single-cell RNA-seq datasets using bioinformatics tools.
- Maintains detailed electronic lab notebooks and prepare figures for presentations manuscripts and progress reports.
- Supports grant proposals by contributing data methods and experimental insights for funded and future applications.
- Mentors and trains research assistants students and rotating trainees in lab techniques and data analysis workflows.
- Presents findings at weekly lab meetings and contribute to Center-wide seminars and collaborative discussions.
Minimum Qualifications
- MD or Ph.D. in Basic Science Health Science or a related field.
- No experience required.
Preferred Qualifications
- Ph.D. in Immunology Cancer Biology Biomedical Engineering Molecular/Cell Biology or a closely related field.
- Hands-on experience in T-cell engineering including lentiviral/retroviral vector design transduction and functional immune assays.
- Proficiency in multi-parameter flow cytometry including panel design compensation and data interpretation.
- Experience with single-cell and bulk RNA-seq workflows including sample preparation and downstream analysis.
- Familiarity with barcoded pooled screening techniques or other high-throughput genetic screens.
- Prior experience with mouse models (e.g. xenograft or humanized models) including tumor monitoring and tissue processing.
- Strong organizational skills attention to detail and commitment to rigorous data documentation and reproducibility.
- Excellent communication and interpersonal skills with a demonstrated ability to work both independently and as part of a collaborative team.
- Experience mentoring junior trainees or contributing to a team-based research environment is a plus.
Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.
PD; SN
Required Experience:
IC
Key Skills
- Virology
- Bioinformatics
- Genetics
- R
- Biochemistry
- Cell Biology
- Research Experience
- Spectroscopy
- Cell Culture
- Molecular Biology
- Microscopy
- Research Laboratory Experience
