Special Project Associate II-Neuroscience-Ikezu lab for Molecular Neurotherapeutics

The Molecular Neurotherapeutics Laboratory directed by Drs. Ikezu studies molecular and cellular mechanisms underlying aging and neurodegenerative disorders including Alzheimers disease (AD) and frontotemporal dementia with a particular focus on neuroimmunology. We are interested in investigating the pathological function of small extracellular vesicles (EVs) which are known to transfer abnormal proteins as vehicles inside the brain. Our mission is to decipher the molecular machinery of EVs which could be a future therapeutic target of AD and frontotemporal dementia or aging process.

The Ikezu lab is engaged in multiple arrays of cutting-edge technologies including behavioral studies adeno-associated virus gene delivery fluorescence activated cell sorting proteomics RNA sequence super resolution confocal microscopy. The successful candidate will perform daily laboratory activities including iPSC cell culture animal colony maintenance histology EV flow cytometry and other general laboratory inventory work. The incumbent will also assist in brain sample cryosectioning immunohistochemistry sample processing data collection using confocal microscope and analysis using IMARIS software.

We are looking for a highly self-motivated and organized individual to join our team. The successful candidate will have a passion for science an inquisitive mind and a strong interest to learn and implement new knowledge. Basic laboratory math and computer skills as well as attention to detail are a must. Experience with animal work molecular cell biological and/or biochemical techniques is an advantage. We provide a supportive environment and is committed to offering individualized training mentoring and career development opportunities.

For more details see our lab homepage: candidate will perform daily laboratory activities including animal colony maintenance histology EV flow cytometry and other general laboratory inventory work. The incumbent will also assist in brain sample cryosectioning immunohistochemistry sample processing data collection using confocal microscope and analysis using IMARIS software.

The position is considered non-exempt (hourly) and therefore all hours worked must be recorded. A Special Project Associate at Mayo Clinic is a temporary position intended to execute experimental studies in support of lab goals and grant commitments as designated by the Principal Investigator. Proof of English proficiency is required for J-1 Short-Term Scholars Research Scholars Professors Specialists and Student Interns sponsored by Mayo Clinic. The following is required for completeness of application: Current curriculum vitae with bibliography Proof of highest degree received (if awarded a bachelors or masters degree). Please also be prepared that you may be asked to provide two letters of recommendation to the hiring PI prior to an interview.

Bachelors degree required and experience required in lab project or research work in an educational or work setting. Candidate must have a solid understanding of lab techniques equipment and safety. Math and computer skills as well as attention to detail are a must. Experience with animal work molecular cell biological and/or biochemical techniques is an advantage.