Director, Global Sigvotatug

ROLE SUMMARY

At Pfizer Oncology we are committed to Outdo Cancer by advancing transformative medicines wherever we can make a profound difference in the lives of patients. Today Pfizer Oncology has an industry-leading pipeline that includes the combined legacy Pfizer and Seagen portfolio across breast genitourinary hematology-oncology and thoracic therapeutic areas. Thoracic represents a crucial component to achieve Pfizers overarching strategic ambition in Oncology; thoracic is estimated to represent 25% of Pfizer Oncologys 2030 global sales. Collectively our focus is on building upon our foundation in lung precision medicine to accelerate new standards of care in broader populations.

Despite therapeutic advances in lung cancer there remains significant unmet patient need. Each year there are 2.7 million new lung cancer cases globally. The lung cancer therapies market is expected to grow from $45B in 2025 to $70B in 2030 globally.

Core to Pfizers lung cancer strategy is realizing the potential of our first-in-class antibody drug conjugates (ADCs) namely our potential first-in-class integrin-Beta-6 (IB6)-targeting ADC sigvotatug (SV). >90% of NSCLC tumors express integrin Beta-6. The first commercial launch of SV in lung cancer specifically 2L NSCLC is being planned for 1H 2027; followed by 1L NSCLC PD-L1 TPS >50% in 2H 2028. SV is also being studied in 1L NSCLC (any PD-L1 TPS).

In Global Marketing we translate science into value for patients. Our remit is to own the strategic direction across the asset lifecycle ensure long-term value creation and preservation and drive brand consistency across markets and efficiencies in execution.

This role will report to the Global Commercial Lead for SV.

ROLE RESPONSIBILITIES

• Partner with US and International commercial colleagues Global Medical Affairs Global Access & Value PGS and Regulatory to ensure global launch readiness for SV
• Lead delivery of Global Integrated Launch Strategy (ILS)
• Establish launch sequence with markets and Regulatory and ensure GPT endorsement of key changes to launch sequence
• Coordinate with US/ICO/select markets to track launch performance and launch readiness in DLPP and escalate key issues
• Drive OGSM KPI development and ensure launch metrics are thoughtfully developed and aligned with US and International; update key leadership dashboards (e.g. Launch Health Report)
• Execute cross-functional and Global/US/ICO launch readiness meeting(s)
• Partner with Thought Leader Strategy Lead and Global Medical Affairs to develop Global SV KOL Engagement Strategy
• Collaborate effectively with R&D Regulatory Global Access & Value Global Medical Affairs Customer Analytics & Insights Finance PGS US and International.
• Conduct all activities and make decisions that are in accordance with Company policies and SOPs Pfizer Values & global regulatory guidelines and requests consultation when navigating uncertain situations.

BASIC QUALIFICATIONS

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers develop and coach others oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

• Bachelors degree and 8 years of commercial experience in the pharmaceutical industry
• Marketing experience
• Strong strategic thinking analytical skills detail and action oriented creative flexible self-motivated
• Ability to work independently and demonstrates judgement of what needs to be escalated
• Strong team player with demonstrated ability to engage experts from a wide range of functional areas to improve business performance and find a path forward
• Excellent verbal and written communication skills for a wide range of audiences
• Is a role model for the Pfizer Values

PREFERRED QUALIFICATIONS

• Advanced degree
• Global or US Marketing experience is required

NON-STANDARD WORK SCHEDULE TRAVEL OR ENVIRONMENT REQUIREMENTS

Ability to travel approximately 20% of the time

Other Job Details:

Last Date to Apply for Job: November 24th 2025

Additional Location Information: New York NY; Collegeville PA; Cambridge MA; Bothell WA Europe - Any Pfizer Site

Eligible for Relocation Package: No

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Relocation assistance may be available based on business needs and/or eligibility.