Postdoctoral Fellow in ubiquitin biology research
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Job Location:
Monthly Salary:
Posted on:
07-11-2025
Vacancies:
1 Vacancy
Job Summary
Bhogaraju group at EMBL Grenoble has several postdoc positions open to conduct fundamental and translational research into a class of understudied human ubiquitin ligases. Our group explores Melanoma-associated antigen (MAGE)-RING ubiquitin ligases (MRLs) some of which are highly oncogenic. We are looking for passionate and ambitious colleagues who are willing to make significant fundamental discoveries related to the medically relevant MRLs and their ubiquitination substrates.
Our recent work includes the discovery of a conserved ligase-binding cleft in MAGE proteins showcasing (Griffith-Jones et al. 2024). We also developed a proteomics-based ubiquitin ligase-substrate mapping method known as Ub-POD which is being widely used in the field (Mukhopadhyay et al. 2024). Bhogaraju group uses Proteomics cell biology and structural biology methods to study human ubiquitin ligases especially MRLs. See further information at lab webpage profile
Required qualifications:
- A PhD in Biochemistry/Cell biology or related field
- At least one first author research article/preprint
- Strong understanding of quantitative proteomics and its applications
- Proficiency in common molecular biology and cell biology techniques
- Immunofluorescence microscopy
- CRISPR/Cas9- based cell engineering
- Experience in Lentiviral transductions
Preferred qualifications:
- Expertise in mass spectrometry data analysis
- Basic understanding of protein structural biology and Protein structure analysis
- Alphafold
- Cancer biology background and translational research
Preferred personal attributes:
- Strong team player with willingness to collaborate
- Proactive in decision-making
- Critical thinker with strong problem-solving abilities
Contract length:2 years ( with the possibility of extension)
Salary: Monthly stipend (first year): 3.64624 (after tax excl. pension & insurances) benefits
Professional development support
The EMBL Fellows Career Service provides support and guidance to predoctoral and postdoctoral fellows across all six EMBLs sites.
Working with a dedicated Careers Advisor this invaluable service will help you to take informed decisions about your career planning both in the short and longer term. Whether your main interest is pursuing a career path in academia exploring opportunities in industry or exploring an independent venture the EMBL Fellows Career Service with provide you with a portfolio of activities and resources to help you.
To find out more please visit - EMBL-fellows-career-service
Why join us
Join a culture of innovation
We are located on the Wellcome Genome Campus alongside other prominent research and biotech organisations and surrounded by beautiful Cambridgeshire countryside. This is a highly collaborative and inclusive community where our employees enjoy a relaxed atmosphere. We are committed to ensuring our employees feel valued supported and empowered to reach their professional potential.
Enjoy lots of employee benefits:
Financial incentives:Monthly family and child allowances generous stipend reviewed yearly pension scheme death benefit and unemployment insurances
Flexible working arrangements including hybrid working patterns
Private medical insurancefor you and your immediate family
Generous time off:30 days annual leave per year in addition to public holidays
Campus life:Free shuttle bus to and from work (Heidelberg) on-site library subsidised on-site gym and cafeteria casual dress code extensive sports and social club activities (on campus and remotely)
Family benefits: Kindergarten (Heidelberg) 10 days of child sick leave paid maternity & parental leave holiday clubs on campus and monthly family and child allowances
What else you need to know
International applicants: We recruit internationally and successful candidates are offered visa exemptions. Read more on our page for international applicants.
Diversity and inclusion: At EMBL we strongly believe that inclusive and diverse teams benefit from higher levels of innovation and creative thought. We encourage applications from women LGBTQ & individuals from all nationalities.
Job location: All our fellowships are based on-site (for at least part of each week). If you are living overseas you will receive a generous relocation package to support you.
EMBL is a signatory of DORA. Find out how we apply DORA principles to our recruitment and performance assessment processes here
How to apply: To apply please submit a cover letter and a CV through our online system. Applications will close at 23:59 CET on the date shown below. We aim to provide a response within two weeks after the closing date.
Closing Date
07/12/2025
Key Skills
- Virology
- Bioinformatics
- Genetics
- R
- Biochemistry
- Cell Biology
- Research Experience
- Spectroscopy
- Cell Culture
- Molecular Biology
- Microscopy
- Research Laboratory Experience
About Company
With 29 member states, laboratories at six locations across Europe and thousands of scientists and engineers working together, the European Molecular Biology Laboratory is a powerhouse of biological expertise. The intergovernmental organisation, headquartered in Heidelberg, was founde ... View more
