Senior Director of IT Quality & Compliance

AstraZeneca is a global innovation-driven BioPharmaceutical business that focuses on the discovery development and commercialisation of prescription medicines for some of the worlds most serious diseases. But were more than one of the worlds leading pharmaceutical companies. At AstraZeneca were dedicated to being a Great Place to Work where you are empowered to push the boundaries of science and unleash your ambitious spirit. Theres no better place to make a difference to patients society and the planet.

As Senior Director IT Quality & Compliance you will play a vital role working within the Strategy Performance and Quality team to safeguard our Licence to Operate. Your focus will be ensuring that our IT systems and services consistently meet the highest standards for quality and complianceparticularly with GxP but also SOx and evolving regulatory requirements. Youll lead a diverse global team dedicated to sustaining operational excellence driving a proactive compliance culture and enabling AstraZeneca to remain at the forefront of change and innovation.

This is both an operationally accountable and forward-looking role. You will balance daily delivery with ongoing transformation and improvement ensuring IT Quality & Compliance is a trusted business partnerenabling innovation while protecting patients products and AstraZenecas reputation.

Accountabilities:

GxP Compliance Excellence:
Lead the development implementation and ongoing improvement of our IT Quality Management System (QMS) ensuring GxP requirements are met or exceeded. Oversee inspection readiness and successful outcomes for regulatory audits and inspections.

SOx Programme Oversight:
Direct IT SOx compliance activitiescovering management testing remediation and coordination for both external and internal auditsthrough a dedicated specialist team.

Protect our Licence to Operate:
Sustain AstraZenecas readiness to meet all regulatory requirements with GxP as the primary focus ensuring a robust and compliant IT landscape at all times.

Global Leadership for Quality & Compliance:
Lead inspire and develop a team of approximately 65 professionals based in 10 countries creating a culture of operational rigor inclusivity high performance and continuous learning.

Operational & Strategic Change:
Deliver daily compliance while proactively driving process improvements digital adoption and transformation that advances AstraZenecas strategic goals.

Stakeholder Engagement:
Represent IT quality and compliance to internal and external partners including regulatory agencies auditors and executive stakeholdersacting as a credible expert and trusted advisor.

Culture & Capability Building:
Champion a resilient values-driven team culture. Invest in developing people building leadership succession and ensuring lasting strength and adaptability across the global function.

Essential Skills & Experience

• Extensive experience leading global quality or compliance teamspreferably spanning multiple regions or time zonesin a highly regulated pharmaceutical biotechnology or life sciences environment.

• Deep hands-on expertise with GxP regulatory frameworks (e.g. FDA EMA MHRA) including implementation and management of IT QMS and successful regulatory inspection outcomes.

• Demonstrated track record managing IT SOx/financial controls compliance programmes including direct involvement in audit cycles and external auditor engagement.

• Operational accountability for sustaining compliance and licence to operate alongside proven capability to deliver strategic change and transformation.

• Outstanding people leadership skills including experience of matrix management building international teams and developing high-performing inclusive cultures.

• Excellent proven communication influencing and collaboration skills with the ability to operate effectively at all levelsinternally and externally.

• Proven strong judgment and pragmatic decision-making in balancing compliance quality and business needs.

• Resilience calm and tenacity under pressure with the capability to manage urgent compliance challenges alongside long-term strategic objectives.

Desirable Skills & Experience

• Experience leading digital transformation or significant change initiatives in quality or compliance functions.

• Additional professional qualifications (e.g. ISPE PCC CPIP ISACA CISM) are advantageous.

• Exposure to IT infrastructure or application development and/or cross-functional leadership in technology-enabled settings.

When we bring together diverse teams we spark bold thinking and the power to inspire life-changing medicine. Our hybrid working approach blends the benefits of in-person collaboration (a minimum average of three days per week in the office) with flexibility to support each individuals way of working.

When we put unexpected teams in the same room we unleash bold thinking with the power to inspire life-changing -person working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Join us at a crucial stage of our journey in becoming a digital and data-led enterprise. Make the impossible possible by building partnerships and ecosystems creating new ways of working and driving scale and speed to deliver exponential growth. Focused and committed and backed with the investment to succeed were driving cross-company change to disrupt the entire industry. Be part of a team that has the backing to innovate disrupt an industry and change lives. Were a network of entrepreneurial self-starters who contribute to something far bigger.

Are you ready to make a difference Apply today and join us in our mission to improve global public health!

We welcome your applications not later than 7th November 2025.

Date Posted

Closing Date