Analytical Chemistry Postdoctoral Researcher

We are seeking a highly motivated Analytical Chemistry Postdoctoral Researcher to join our dynamic team and play a key role in pushing the boundaries of analytical chemistry with advanced LC-MS techniques. Tackle complex analytical challenges using state-of-the-art instrumentation and innovative approaches. Lead method development for both targeted and untargeted analyses apply high-resolution mass spectrometry for structural elucidation and contribute to research projects with significant real-world impact.

As part of our multidisciplinary group you will collaborate with experts in chemistry biology and forensic science leveraging your LC-MS expertise to address research needs of national security importance. Your work will directly support unique federal law enforcement efforts performing forensic analysis and conducting critical R&D with high-impact consequences. This position offers hands-on experience with groundbreaking technologies providing a platform for publishing your discoveries and opportunities to expand your expertise in small molecule and proteomic analyses. The role is based in the Forensic Sciences and Assessment Group of the Nuclear and Chemical Sciences Division within the Physical and Life Sciences Directorate and is matrixed to LLNLs Forensic Science Center a national security asset with expertise in state-of-the-art analytical forensic chemistry.

This position requires full-time on-site presence due to the nature of the work.

You will 

• Exploit diverse real-world samples by unraveling the molecular composition and forensic meaning of complex unknown materials using high-resolution mass spectrometry and advanced data analytics.
• Drive innovation by collaborating with scientists planning experimental campaigns and coordinating resources to deliver breakthrough research outcomes.
• Research design and execute targeted and untargeted chemical analyses across a wide range of analytes.
• Pursue independent complementary research interests including writing prospective proposals engaging with a broad network of scientists within and outside the laboratory.
• Develop research plans interpret results and communicate findings through peer-reviewed publications technical reports and presentations for internal and external audiences including sponsors stakeholders and scientific conferences.
• Operate maintain and troubleshoot analytical instrumentation (HPLC/UHPLC LC-MS and associated detection technologies).
• Maintain detailed and accurate laboratory notebooks documenting all processes and procedures and ensure compliance with ethical institutional regulatory and safety policies.
• Perform additional duties as assigned.

Qualifications :

• Ability to obtain and maintain a U.S. Department of Energy Q-level security clearance (U.S. Citizenship required).
• PhD in Chemistry Biology Forensic Science or a related field.
• Experience with applied organic mass spectrometry particularly in developing and utilizing LC-MS methods including high-resolution mass spectrometry (e.g. Orbitrap or TOF) and MS/MS techniques.
• Familiarity with complimentary spectrometric techniques (e.g. GC-MS) and analytical methodologies (NMR IR UV).
• Advanced organization and time-management skills with adaptability to dynamic research priorities and the ability to multi-task and meet deadlines.
• Proven ability to work independently and collaboratively within multidisciplinary teams.
• Excellent verbal written and interpersonal communication skills for effective interaction with scientists engineers and technical/administrative staff.
• Demonstrated ability to conduct independent research as evidenced by peer-reviewed publications.

Qualifications We Desire

• Experience with forensic laboratory operations including ISO17025 quality management requirements.
• Advanced skills in chromatographic separations LC-MS method optimization and application to diverse molecular classes (small molecules peptides proteins).
• Experience with untargeted analysis to identify small molecules peptides and proteins of interest including de novo proteomics.
• Demonstrated success in presenting and publishing research to broad scientific and stakeholder audiences.
• Familiarity with data analysis workflows chemometrics or bioinformatics relevant to analytical chemistry.

Additional Information :

#LI-Onsite

Position Information

This is a Postdoctoral appointment with the possibility of extension to a maximum of three years open to those who have been awarded a PhD at time of hire date.

Why Lawrence Livermore National Laboratory

• Included in 2025 Best Places to Work by Glassdoor!
• Flexible Benefits Package
• 401(k)
• Relocation Assistance
• Education Reimbursement Program
• Flexible schedules (*depending on project needs)
• Our values - visit  Clearance

  This position requires a Department of Energy (DOE) Q-level clearance.  If you are selected we will initiate a Federal background investigation to determine if you meet eligibility requirements for access to classified information or matter. Also all L or Q cleared employees are subject to random drug testing.  Q-level clearance requires U.S. citizenship. 

  Pre-Employment Drug Test

  External applicant(s) selected for this position must pass a post-offer pre-employment drug test. This includes testing for use of marijuana as Federal Law applies to us as a Federal Contractor.

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  Remote Work :

  No

  
  

  Employment Type :

  Full-time