Research Scientist
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Job Location:
Washington DC, WA - USA
Monthly Salary:
Not Disclosed
Posted on:
10-10-2025
Vacancies:
1 Vacancy
Job Summary
Job Description
The Sahoo Lab is seeking a Research Scientist to help develop and lead our research program focused on the genetic and functional mechanisms driving bone marrow failure clonal hematopoiesis and progression to MDS/AML. The Research Scientist will have the opportunity to pursue an independent project while also contributing to collaborative efforts across the group including mentoring and training junior scientists.
Our lab uses patient-derived samples iPSC models CRISPR-based genome editing single-cell multi-omics and mouse disease models to uncover how germline and acquired genetic changes including mutations and chromosomal aneuploidy shape hematopoietic stem cell fate and leukemogenesis.
Available projects include:
1. Germline predisposition to MDS/AML: Defining the mechanisms by which germline SAMD9L mutations cause hematopoietic failure and predispose to leukemogenesis.
2. Chromosome 7 aneuploidy syndromes: Modeling monosomy 7associated bone marrow failure and understanding its contribution to clonal selection.
3. Clonal evolution and therapeutic vulnerabilities: Using single-cell sequencing platforms to track clonal evolution and identify novel therapeutic targets in high-risk MDS/AML.
The Research Scientist will have access to Virginia Tech and Childrens National Hospital resources core facilities and seminars and will be provided strong opportunities for career growth and development. Our team actively supports diverse career trajectories and encourages leadership training networking conference participation and skill development. This is an exciting opportunity to play a foundational role in shaping a new lab at the Research and Innovation Campus in Washington DC.
Required Qualifications
Ph.D. in a biological science such as hematology genetics molecular biology or cancer biology
Demonstrated postdoctoral research experience with strong publication record
Strong expertise in experimental design and execution
Proficiency in wet lab techniques including molecular biology and mammalian cell culture
Hands-on experience working with primary cells such as iPSCs and hematopoietic stem cells
Experience with CRISPR-based genome editing and functional screens
Self-motivated creative and detail-oriented researcher
Excellent organizational and time management skills
Ability to work independently and as part of a collaborative team
Experience mentoring or training students and/or research staff
Excellent communication skills
Preferred Qualifications
Experience with mouse models of hematopoiesis or cancer
Familiarity with single-cell multi-omics approaches
Analysis of large scale genomic and/or transcriptomics data sets
Overtime Status
Exempt: Not eligible for overtime
Appointment Type
Restricted
Salary Information
Commensurate with experience
Hours per week
40
Review Date
10/21/25
Additional Information
The successful candidate will be required to have a criminal conviction check.
About Virginia Tech
Dedicated to its mottoUt Prosim(That I May Serve) Virginia Tech pushes the boundaries of knowledge by taking a hands-on transdisciplinary approach to preparing scholars to be leaders and problem-solvers. A comprehensive land-grant institution that enhances the quality of life in Virginia and throughout the world Virginia Tech is aninclusive communitydedicated to knowledge discovery and creativity. The university offers more than 280 majors to a diverse enrollment of more than 36000 undergraduate graduate and professional students in eightundergraduate colleges aschool of medicine aveterinary medicinecollegeGraduate School andHonors College.The university has a significant presence across Virginia including Blacksburg the greater Washington D.C. area the Health Sciences and Technology Campus in Roanoke sites in Newport News and Richmond and numerousExtension officesandresearch institutes.A leading global research institution Virginia Tech conducts more than $650 million in research annually.
Virginia Tech endorses and encourages participation in professional development opportunities and university shared governance. These valuable contributions to university shared governance provide important representation and perspective along with opportunities for unique and impactful professional development.
Virginia Tech does not discriminate against employees students or applicants on the basis of age color disability sex (including pregnancy) gender gender identity gender expression genetic information ethnicity or national origin political affiliation race religion sexual orientation or military status or otherwise discriminate against employees or applicants who inquire about discuss or disclose their compensation or the compensation of other employees or applicants or on any other basis protected by law.
If you are an individual with a disability and desire an accommodation please contact Brittany Sheltonat during regular business hours at least 10 business days prior to the event.
Key Skills
- Laboratory Experience
- Machine Learning
- Python
- AI
- Bioinformatics
- C/C++
- R
- Biochemistry
- Research Experience
- Natural Language Processing
- Deep Learning
- Molecular Biology
About Company
About Johnson & Wales University: Founded in 1914, Johnson & Wales University is a private, nonprofit, accredited institution with campuses in Providence, Rhode Island, and Charlotte, North Carolina.
