Research Services Entry Professional

University of Colorado Anschutz Medical Campus

Department: Biochemistry & Molecular Genetics

Job Title: Research Services Entry Professional

Position # Requisition #37908

Job Summary:

A Research Services Entry Professional position is available in the laboratory of Francisco J. Asturias in the Department of Biochemistry and Molecular Genetics at the University of Colorado Anschutz Medical Campus. The Asturias group works on structural (cryo-EM) biochemical and mechanistic studies of macromolecular complexes involved in various essential cellular processes. The person in this position will be focused on mechanistic and structural characterization of the transcriptional Mediator complex with emphasis on understanding the regulation of Mediators functional interactions with other components of the eukaryotic transcription machinery. Studies will center around biochemical and molecular biology approaches with likely extension to cryo-EM studies. Applicants with background in general biochemistry and molecular biology and experience in recombinant protein expression and purification would be particularly well qualified. This position reports directly to Dr. Asturias. The applicant will receive training and acquire expertise in all experimental approaches used in the Asturias lab.

The person in this position must be highly motivated and well-organized and capable of working both independently and as a member of a research team. They will be expected to interact and collaborate with other members of the Asturias lab and with collaborators at CU Anschutz and beyond. Good troubleshooting skills and ability to interpret organize and communicate experimental data are a must.

Key Responsibilities:

• Conduct biochemical and structural studies of Mediator. This might include work on mammalian cell culture CRISPR/Cas9 protein expression/purification biochemical studies preparation and automated imaging of cryo-EM specimens EM image analysis using various software packages EM map and atomic model refinement.

• Summarize interpret and communicate experimental results

• Writing of scientific papers for peer-reviewed journals

• Presentation of research at meetings and conferences

• Initiating and maintaining relationships with collaborators including coordination of experimental work

This description is a summary only and describes the general level of work being performed it is not intended to be all-inclusive. The duties of this position may change from time to time and/or based on business need. We reserve the right to add or delete duties and responsibilities at the discretion of the supervisor and/or hiring authority.

Work Location:

Onsite this role is expected to work onsite and is located in Aurora CO.

Why Join Us:

Our department conducts research across a wide biological scale for fundamental scientific understanding with applications to many disease contexts. The overarching goal is to reach a level of molecular insight that helps develop therapeutic approaches to disease.

As biochemists and molecular geneticists we are amid an unprecedented time of discovery - our conception of the molecular biology of cells is going from the equivalent of grainy black-and-white to high-resolution technicolor. From deciphering the choreography of transcription complexes chromosomes and RNA molecules within cells to developing novel approaches to 3D molecular structure determination to understanding how viruses hijack a cells machinery and alter its metabolome the researchers in Biochemistry and Molecular Genetics (BMG) are at the forefronts of their fields both conceptually and technologically.

Why work for the University

We haveAMAZINGbenefits and offerexceptional amounts of holiday vacation and sick leave! The University of Colorado offers an excellent benefits package including:

• Medical: Multiple plan options

• Dental: Multiple plan options

• Additional Insurance: Disability Life Vision

• Retirement 401(a) Plan: Employer contributes 10% of your gross pay

• Paid Time Off: Accruals over the year

• Vacation Days: 22/year (maximum accrual 352 hours)

• Sick Days: 15/year (unlimited maximum accrual)

• Holiday Days: 10/year

• Tuition Benefit: Employees have access to this benefit on all CU campuses

• ECO Pass: Reduced rate RTD Bus and light rail service

There are many additional perks & programs with the CU Advantage.

Qualifications:

Minimum Qualifications:

• Bachelors degree in biology molecular biology chemistry genetics or related field

Applicants must meet minimum qualifications at the time of hire.

Preferred Qualifications:

• Masters degree in biology molecular biology chemistry genetics or related field

• Prior experience or background within an experimental or wet laboratory

Knowledge Skills and Abilities:

• Knowledge of basic laboratory techniques including safety procedures and techniques

• Ability to communicate effectively both in writing and orally

• Ability to establish and maintain effective working relationships with employees at all levels throughout the institution

• Outstanding customer service skills

• Knowledge of basic human anatomy physiology medical terminology

• Ability to interpret and master complex research protocol information

How to Apply:

For full consideration please submit the following document(s):

1. Curriculum vitae / Resume

2. Three to five professional references including name address phone number (mobile number if appropriate) and email address

Questions should be directed to: Francisco Asturias

Screening of Applications Begins:

Screening begins immediately and continues until (Five Days from Posting).

Anticipated Pay Range:

The starting salary range (or hiring range) for this position has been established as $46274 - $58861.

The above salary range (or hiring range) represents the Universitys good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation depending on the level.

Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave health plans and retirement contributions that add to your bottom line.

Total Compensation Calculator

Equal Employment Opportunity Statement:

CU is an Equal Opportunity Employer and complies with all applicable federal state and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity and we encourage individuals from all backgrounds to apply including protected veterans and individuals with disabilities.

ADA Statement:

The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act please contact the Human Resources ADA Coordinator at .

Background Check Statement:

The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty staff students and visitors. To assist in achieving that goal we conduct background investigations for all prospective employees.

Vaccination Statement:

CU Anschutz strongly encourages vaccination against the COVID-19 virus and othervaccine preventable diseases. If you work visit or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work visit or volunteer addition if you work in certain research areas or perform certain safety sensitive job duties you must enroll in theoccupational health medical surveillance program.