Research Lab Tech I (Chekuri)

Site: Massachusetts Eye and Ear Infirmary

Mass General Brigham relies on a wide range of professionals including doctors nurses business people tech experts researchers and systems analysts to advance our mission. As a not-for-profit we support patient care research teaching and community service striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.

Job Summary

Summary - Responsible for maintaining laboratory equipment organizing and preparing samples conducting experiments and recording and analyzing data.

Does this position require Patient Care No

Essential Functions
-Perform laboratory experiments following established protocols and procedures.
-Prepare and handle samples reagents and solutions ensuring accuracy and adherence to safety guidelines.
-Operate and maintain laboratory equipment and instruments conducting routine calibration and troubleshooting as needed.
-Record experimental data accurately and maintain organized records of procedures protocols and results.
-Compile and analyze data using appropriate statistical and analytical methods.
-Assist in data interpretation and presentation contributing to research findings and reports.

Education
Bachelors Degree Related Field of Study required

Can this role accept experience in lieu of a degree
Yes

Licenses and Credentials

Experience
Prior laboratory experience either through academic coursework internships or employment 1-2 years preferred

Knowledge Skills and Abilities
- Strong theoretical and practical knowledge of laboratory techniques and procedures.
- Familiarity with common laboratory equipment and instruments used in research experiments.
- Proficiency in data collection analysis and scientific software tools.
- Excellent attention to detail organizational skills and the ability to multitask and prioritize tasks effectively.
- Strong problem-solving skills and the ability to troubleshoot technical issues.
- Excellent written and verbal communication skills to effectively convey experimental procedures results and challenges.

POSITION SUMMARY:

The Grousbeck Gene Therapy Center at Mass Eye and Ear has an open position for a Research Lab Tech to assist in the application of novel gene therapy modalities. The Center provides a dynamic multi-disciplinary environment that pursues the common goal of developing therapeutic gene transfer in future medicine.

We are seeking a Research Lab Tech to join the laboratory of Dr. Anil Chekuri to perform in vivo experiments both in small animal models. The main responsibilities of this position will include animal experimentation and rodent colony management. Familiarity with tissue processing is desirable. Demonstrated excellence in time management and organizational skills are essential. A bachelors degree in biology or related discipline is required.

We offer a flexible and collaborative environment as well as the opportunity to develop scientifically and to explore the promising field of translational AAV gene therapy.

ESSENTIAL FUNCTIONS:

• Animal work (rodents):

• Colony management and animal handling (breeding tagging and genotyping)
• Sub-retinal injections
• Injections (SQ IM RO IV IVT SR IP)
• In vivo imaging and Electroretinography
• Pre-op and post-op care
• Euthanasia/necropsy
• Tissue collection

• Ensure cleanliness of the lab and equipment including instrument maintenance.
• Adherence to pertinent departmental policies practices and procedures (SOPs IACUC Hazardous materials safety procedures and biosafety protocols).
• Keep accurate records of experiments; analyze data and present results to PI.
• Tissue processing (tissue fixation/freezing embedding cryo-sectioning and DNA/RNA extraction) is an asset.
• Molecular cloning of plasmids using PCR restriction digestion and other methods
• Cell and tissue culture.
• Biochemical assays including SDS-PAGE and ELISA.

EDUCATION AND EXPERIENCE:

• BS/BA in biology or related discipline
• Experience in or willing to learn vivo rodent manipulation (including colony management injections and necropsies).
• Experience in or willing to learn Optical coherence tomography fundus imaging and in vivo bioluminescence imaging.
• Must be able to work as part of a team.
• Excellent time management and organization.

WORKING CONDITIONS:

Work will primarily take place in a research laboratory setting. Job may require exposure to bio-hazardous or toxic substances.

HIPAA Privacy Training and Sanctions

All employees who have access to health information whose confidentiality is protected by the HIPAA Privacy Rule are required by the Rule to receive training so that they have an understanding and knowledge of the Privacy Rule that corresponds to their job responsibilities and of the group health plans policies and procedures that impact on their job duties. Training on the requirements of the HIPAA Privacy Rule and the plans health information policies and procedures under the direction of the institutions privacy officer is a pre-requisite for this position.

Employees who violate the requirements of the HIPAA Privacy Rule will be subject to discipline up to and including termination.

This description is intended to indicate essential tasks and levels of work difficulty that will be required of positions that will be given this title. It is not intended to limit or in any way modify the right of supervisors to assign direct or control the work of staff members under their supervision. The use of a particular expression or illustration describing duties shall not be held to exclude other duties not mentioned but that are of similar kind or level of difficulty

Onsite

20 Staniford Street

40

Regular

Day (United States of America)

Pay Range

$19.76 - $28.44/Hourly

Grade

5

At Mass General Brigham we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive and any offer extended will take into account your skills relevant experience if applicable education certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however it does not encompass all elements contributing to your total compensation addition to competitive base pay we offer comprehensive benefits career advancement opportunities differentials premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.

Massachusetts Eye and Ear Infirmary is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religious creed national origin sex age gender identity disability sexual orientation military service genetic information and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973 the Vietnam Veterans Readjustment Act of 1974 and Title I of the Americans with Disabilities Act of 1990 applicants who require accommodation in the job application process may contact Human Resources at .

Mass General Brigham Competency Framework