Associate Director, PKPD Pharmacometrics NONMEM SAS Programmer
Associate Director, PKPD Pharmacometrics NONMEM SAS Programmer
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Job Description
Job Title: Associate Director PKPD / Pharmacometrics / NONMEM / SAS Programmer
Global Career Level: E
Introduction to role:
Are you interested in shaping the future of drug development We are looking for an Associate Director PKPD / Pharmacometrics / NONMEM / SAS Programmer to join our Clinical Pharmacology and Quantitative Pharmacology Data Programming team. In this position you will be responsible for preparing programming validating and diagnosing data to support Pharmacometrics and Clinical Pharmacology analyses. You will be instrumental in influencing critical decision making throughout all phases of drug development and regulatory interactions.
Accountabilities:
As an Associate Director PKPD / Pharmacometrics / NONMEM / SAS Programmer you will be responsible for expert data cleaning manipulation transformation and integration at both the study and compound level. You will apply advanced data integration techniques that directly contribute to the value of each study and compound. Key responsibilities include pooling data from study and compound-level SDTM/ADaM datasets to prepare analysis-ready data for Pharmacometrics Modeling and Simulation (M&S) software such as NONMEM. This work will play a critical role in informing study design dose selection dose justification and guiding go/no-go decisions. Additionally you will contribute to regulatory documents and internal initiatives that advance the Pharmacometrics discipline and ensure compliance with Good Clinical Practice (GCP) regulations.
Essential Skills/Experience:
10 years of hands-on experience in SAS programming in preparing pooled data sets across studies.
Strong understanding of pharmacokinetics pharmacodynamics and their application in drug development.
Strong SAS/R programming skills
Expert knowledge of data preparation and programming practices (CDISC SDTM ADaM)
Demonstrated data programming and clinical development expertise
Good knowledge of global regulatory compliance processes standards
Capability to develop tools to support data integration & visualization
Bachelors degree MS preferred with relevant experience required
Demonstrated experience in regulatory submissions and interdisciplinary team leadership
Varied programming languages (SAS R Python)
Experience in early and late-stage drug development
Excellent problem-solving communication and project management skills.
Proficient oral and written English communication skills
Knowledge in pharmacology drug targets and core Therapy areas (e.g. Oncology Respiratory Renal Metabolism etc.)
Quantitative/Scientific background (Statistics Engineering Biological Science)
Desirable Skills/Experience:
Demonstrated expertise in data preparation and programming to support Pharmacometrics Modeling and Simulation (M&S) software (e.g. NONMEM Monolix R Matlab)
Scientific publishing in the field on pharmacometrics
When we put unexpected teams in the same room we unleash bold thinking with the power to inspire life-changing -person working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.
At AstraZeneca we are committed to making a difference by fusing data and technology with scientific innovation to achieve breakthroughs in healthcare. Our dynamic environment encourages creativity and bold decision-making as we strive to treat prevent modify and even cure complex diseases. With a focus on collaboration and inclusivity we unite diverse global knowledge to create impactful solutions for patients worldwide. Here curiosity thrives as we explore new ways to handle diseases and push the boundaries of science.
Ready to make an impact Apply now and be part of a team that is transforming the future of healthcare!
Date Posted
16-Sept-2025Closing Date
30-Sept-2025AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds with as wide a range of perspectives as possible and harnessing industry-leading skills. We believe that the more inclusive we are the better our work will be. We welcome and consider applications to join our team from all qualified candidates regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment) as well as work authorization and employment eligibility verification requirements.
Required Experience:
Director
Employment Type
Full-Time
