Associate Scientist I, CGM Discovery

6084-Janssen Research & Development Legal Entity

Job Location:

Spring House, PA - USA

Monthly Salary: Not Disclosed

Posted on: 30+ days ago

Vacancies: 1 Vacancy

Job Summary

At Johnson & Johnsonwe believe health is everything. Our strength in healthcare innovation empowers us to build aworld where complex diseases are prevented treated and curedwhere treatments are smarter and less invasive andsolutions are our expertise in Innovative Medicine and MedTech we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for more at

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biotherapeutics R&D

Job Category:

Scientific/Technology

All Job Posting Locations:

Spring House Pennsylvania United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments finding cures and pioneering the path from lab to life while championing patients every step of the way.

Learn more at internal pre-identified candidate for consideration has been identified. However all applications will be considered.

We are searching for the best talent for an Associate Scientist I.

Purpose: This role will focus on CAR screening and lead selection (CSLS) to support the development of CAR-T cell therapies.

This position offers an exciting opportunity to contribute to the field of CAR-T cell therapy and work alongside a team of passionate scientists advancing cutting-edge treatments targeting hematological and solid tumors.

Key Responsibilities:

Assist in the culture and expansion of primary T cells as well as the generation of CAR-T cells via viral transduction techniques
Support the development and optimization of high- and medium-throughput CAR-T cell manufacturing workflows
Perform flow cytometry-based experiments for cellular characterization and analysis
Perform Droplet Digital PCR (ddPCR) assays and analysis of vector copy numbers (VCN) of CAR T cells
Operate maintain and troubleshoot basic automation systems utilized in cell therapy processes
Identify and resolve technical challenges encountered during laboratory procedures to ensure smooth workflow
Analyze experimental data using software tools such as GraphPad PRISM FlowJo and Microsoft Office Suite
Maintain precise and comprehensive experimental records in electronic laboratory notebooks (ELNs) to ensure reproducibility and compliance
Collaborate with cross-functional team members to refine protocols enhance process efficiency and achieve project milestones
Strictly adhere to safety protocols regulatory standards and laboratory guidelines while performing experiments

Qualifications:

Bachelors degree in Biology Biotechnology Biomedical Engineering or a related field and at least 2 years of laboratory experience (industry experience is preferred).
Or a Masters Degree in Biology Biotechnology Biomedical Engineering or a related field with at least a year of laboratory experience.
Hands-on experience with Pipetting (single and multi-channel pipettes) aseptic cell culture cell banking with a strong preference for experience working with primary immune cells.
Experience with multicolor Flow Cytometry is required.
Experience with ddPCR and VCN assays is highly preferred.
Experience working in BSL2 and BSL2 labs; familiarity with viral transduction techniques is highly desirable.
Exposure to automation technologies used in laboratory workflows is preferred.
Basic proficiency with data analysis tools and software such as GraphPad PRISM FlowJo and Microsoft Office.
Strong organizational abilities and attention to detail with a demonstrated ability to maintain clear and accurate records.
Effective communication and interpersonal skills to succeed in a collaborative team setting.
Motivated and ability to learn new techniques perform multiple tasks simultaneously.
Authorization to work in the United States indefinitely without restriction or sponsorship.
Availability to work on-site in Spring House PA during standard business hours.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity age national origin disability protected veteran status or other characteristics protected by federal state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants needs. If you are an individual with a disability and would like to request an accommodation please email the Employee Health Support Center () or contact AskGS to be directed to your accommodation resource.

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Required Experience:

Director