Computational Researcher
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Job Location:
Memphis, TN - USA
Yearly Salary:
$ 65520 - 114400
Posted on:
30+ days ago
Vacancies:
1 Vacancy
Job Summary
The Lead Discovery Informatics (LDI) Center in the Department of Chemical Biology and Therapeutics (CBT) led by Dr. Anang Shelat and the Laboratory of Dr. Christoph Gorgulla in the Department of Structural Biology are seeking a highly motivated computational chemist interested in applying state-of-the-art techniques in computer-aided drug design to discover novel small molecule modulators of targets relevant to pediatric disease. The applicant is expected to work alongside domain experts in the biology of pediatric disease chemists and pharmacologists as well as the various institutional shared resources devoted to translational science in a collaborative project team environment.
The applicant must have a strong background in computational chemistry including molecular dynamics simulations virtual screening quantitative structure activity relationship modeling and chemical informatics. The applicant must also be comfortable using high performance computing resources; and developing maintaining and mining chemical and biological databases. Experience with designing proximity-based small molecule modulators such as PROTACs and molecular glues is welcome. Proficiency in scientific computing languages such as R and python and open-source programing tools such as Knime RDKit and ChemProp is a plus.
LDI is a world-class collaborative research center with expertise in chemical informatics molecular simulation computer-aided molecular design and chemically aware machine learning. Our mission is to enable a deeper interrogation of biology through the integration of chemistry computation and data science. The Gorgulla lab has pioneered the development of next generation methods for computational biology and ligand/drug discovery based on ultra-large virtual screenings artificial intelligence quantum chemistry and quantum computing. Individuals with bold vision and who demonstrate excellence in research at the interface of chemistry biology and medicine are encouraged to join our team.
Job Responsibilities:
- Perform data analysis independently using established techniques/methods.
- Set up tools and troubleshoot analyses using new or modified techniques.
- Accurately record/document/share code.
- Prepare and report results/ data leading to posters presentations or publications.
- Performs other duties as assigned to meet the goals and objectives of the department and institution.
- Maintains regular and predictable attendance.
Minimum Education and/or Training:
- Bachelors in Bioinformatics Molecular Biology Biochemistry Computer Science or related field
- Masters degree preferred.
Minimum Experience:
- Bachelors degree and 2 years of relevant experience.
- No experience required with masters degree.
Compensation
In recognition of certain U.S. state and municipal pay transparency laws St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets experience and training licensure and certifications and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $65520 - $114400 per year for the role of Computational Researcher.Explore our exceptional benefits!
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Key Skills
- Intelligence Community Experience
- Python
- Spss
- Microsoft Word
- R
- Regression Analysis
- Windows
- Stata
- Microsoft Powerpoint
- Research Experience
- Data Modeling
- Writing Skills
About Company
A leading children’s hospital, St. Jude treats the toughest childhood cancers and pediatric diseases. Learn about patient referrals, and donate so families never receive a bill for treatment, travel, housing or food.
