Senior Biomarker Scientist, BioX Genetics and Genomics Chapter
Senior Biomarker Scientist, BioX Genetics and Genomics Chapter
Employer Active
Job Alert
You will be updated with latest job alerts via email
Share
Job Alert
You will be updated with latest job alerts via email
Not Disclosed
Salary Not Disclosed
1 Vacancy
Job Description
At Roche you can show up as yourself embraced for the unique qualities you bring. Our culture encourages personal expression open dialogue and genuine connections where you are valued accepted and respected for who you are allowing you to thrive both personally and professionally. This is how we aim to prevent stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche where every voice matters.
The Position
A healthier future. Its what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love.
Thats what makes us Roche.
Roche pREDs BioX Genetics & Genomics (G&G) team within the Pharmaceutical Sciences (PS) organization is seeking a highly skilled and motivated Senior Biomarker Scientist to drive cutting-edge genetic and genomics research. Based in Basel within our BioX Genetics and Genomics Chapter you will lead the development and implementation of advanced genomic solutions for early clinical trials and preclinical safety studies across diverse disease areas.
This impactful role offers a chance to provide matrix leadership leveraging your creative ideas and deep technological insights to deliver high-quality decision-enabling data in early drug development.
The opportunity
As a senior and engaged Biomarker Scientist you will:
Collaborate with cross-functional teams to design and execute biomarker studies
Lead the development validation and implementation of clinical genetics and genomics assays for novel therapeutics (e.g. small molecules large molecules gene therapies) across therapeutic areas like Cardiovascular & Metabolic Neuroscience Ophthalmology Oncology and Immunology.
Manage technology/assay transfers and ensure assay reliability with CRO partners.
Provide translational safety assessments offering mechanistic insights for various drug modalities (eg. siRNAs and Antisense Oligonucleotides).
Innovate by evaluating and applying novel genetics and genomics technologies to maximize insights from precious samples.
Enhance scientific reputation through data interpretation presentations and publications.
Mentor junior scientists and manage external collaborations.
Who You Are
A PhD MD or equivalent in molecular biology biochemistry genomics or a related field with 5 years of experience in clinical genomics assay development within pharma (preferred) biotech or academia.
Extensive experience in the development validation implementation and GLP-quality reporting of clinical (genetic and genomic) biomarker assays and related understanding of regulations.
Deep expertise in tissue processing qPCR/ddPCR NGS RNA profiling single-cell RNAseq spatial transcriptomics and multi-omic approaches.
Strong knowledge of bioinformatic tools for genomic data analysis and interpretation; expertise in population genetics is a plus.
Familiarity with preclinical safety strategies is a plus.
A strategic mindset self-initiative and strong accountability with an ability to challenge be challenged and continuously learn
A collaborative spirit thriving in an agile matrix environment simplifying complexity and prioritizing for patient impact.
We offer an impactful role in a state-of-the-art genetics and genomics team at Roche pRED. You will have opportunities to shape pre-clinical safety early clinical trials and precision medicine in a collaborative interdisciplinary research environment. We offer a competitive salary excellent benefits and professional development opportunities.
Join us in shaping the future of healthcare through genomics and cutting-edge science.
Who we are
A healthier future drives us to innovate. Together more than 100000 employees across the globe are dedicated to advance science ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities foster creativity and keep our ambitions high so we can deliver life-changing healthcare solutions that make a global impact.
Lets build a healthier future together.
Roche is an Equal Opportunity Employer.
Required Experience:
Senior IC
Employment Type
Full-Time
