drjobs Research Scientist, Functional Assay Development

Research Scientist, Functional Assay Development

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1 Vacancy
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Job Location drjobs

San Francisco, CA - USA

Yearly Salary drjobs

$ 130 - 150

Vacancy

1 Vacancy

Job Description

Labcorp Genetics (formerly Invitae) is dedicated to bringing comprehensive genetic information into mainstream medicine to improve healthcare for billions of people!

Our team is driven to make a difference for the patients we serve.

We are leading the transformation of the genetics industry by making clinical-grade genetic information affordable and accessible to guide health decisions across all stages of life.

We have an excellent career opportunity for a Research Scientist Assay Development to join our growing team in San Francisco CA!

This position is not eligible for visa sponsorship

Position Summary

The Genetic Insights Group is a team of biologists machine learning engineers and clinical geneticists who develop tools to define variant effects. We are hiring a Research Scientist for functional assay development to support the Cellular Evidence Platform (CEP) a quantitative scalable and mechanistic assay that generates novel insight into how genetic variation may impact human health. The successful candidate will have extensive expertise in functional genomics in mammalian systems proficiency with handling processing and interpreting large bioinformatic datasets an enthusiasm for working in collaborative and cross-disciplinary environments and a strong interest in applying the power of genetics to advance personalized medicine.


Responsibilities:

  • Foster a continually developing understanding of the practice and promise of functional variant modeling

  • Execute the CEP workflow including variant library cloning cell engineering single-cell capture and cDNA synthesis library preparation and sequencing and data processing

  • Creatively troubleshoot challenges with the experimental platform

  • Collaborate with a cross-functional group of scientists bioinformaticians software engineers and product managers

  • Contribute to the management and maintenance of the research and tissue culture labs

  • Communicate results to project leaders

  • Maintain detailed and organized records within our ELN

Requirements:

  • PhD degree in biological science

  • Technical knowledge of human genetics next generation sequencing and bioinformatics

  • Deep domain expertise in next-generation sequencing applications especially scRNA-seq as well as first-hand experience with multiple sequencing platforms (i.e. Illumina and PacBio)

  • Command of all standard molecular biology procedures including recombinant DNA technologies cloning microbiology and the manipulation and quantification of gene expression

  • Bioinformatic skills sufficient for running the scripts that transfer and process large datasets

Preferred Qualifications:

  • Meticulous creative and independent scientist with a proven track record of applying functional genomics technologies in mammalian cell systems

  • Exceptional capabilities in mammalian tissue culture. Experience includes human iPSCs and immune cell types.

  • Ability to use Python to run and debug bioinformatics pipelines for single-cell data analysis

  • Effective communication and presentation skills within the project team and to stakeholders

  • Dedicated commitment to advancing our multidisciplinary teams objectives

Pay Range: $130k - $150k annual salary (USD)

All job offers will bebased on a candidates skills and prior relevant experience applicabledegrees/certificationsas well as internal equity and market data.

The position is also eligible for an annual bonus under the Labcorp Bonus are payable based on corporate and/or business segment performance and are subject to individual performance modifiers.

Benefits: Employees regularly scheduled to work 20 or more hours per week are eligible for comprehensive benefits including: Medical Dental Vision Life STD/LTD 401(k) Paid Time Off (PTO) or Flexible Time Off (FTO) Tuition Reimbursement and Employee Stock Purchase Plan. Casual PRN & Part Time employees regularly scheduled to work less than 20 hours are eligible to participate in the 401(k) Plan only. For more detailed information pleaseclick here.

Why People choose to work at Labcorp:
At Labcorp it is our people that make us great it is what our clients our partners and most importantly what our employees say. Here you will have the opportunity to collaborate with extraordinary people with diverse viewpoints. You will discover your own outstanding potential as we build an even stronger organization with industry leaders from early development to the clinic and help our clients develop medicines that improve health and improve lives of their family and friends.

Labcorp is proud to be an Equal Opportunity Employer:

Labcorp strives for inclusion and belonging in the workforce and does not tolerate harassment or discrimination of any kind. We make employment decisions based on the needs of our business and the qualifications and merit of the individual. Qualified applicants will receive consideration for employment without regard to race religion color national origin sex (including pregnancy childbirth or related medical conditions) family or parental status marital civil union or domestic partnership status sexual orientation gender identity gender expression personal appearance age veteran status disability genetic information or any other legally protected characteristic. Additionally all qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law.

We encourage all to apply

If you are an individual with a disability who needs assistance using our online tools to search and apply for jobs or needs an accommodation please visit ouraccessibility siteor contact us atLabcorp Accessibility. Formore information about how we collect and store your personal data please see ourPrivacy Statement.

Employment Type

Full-Time

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