Executive Medical Director, US Medical Affairs Lead

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Job Description

JOIN AMGENS MISSION OF SERVING PATIENTS

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year.

As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our award-winning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Executive Medical Director US Medical Affairs Lead

Live

What you will do

Lets do this. Lets change the this vital role as Executive Medical Director US Medical Affairs Lead you will be accountable for the development and execution of the US medical affairs strategy for the Thyroid Eye Disease franchise (teprotumumab-trbw/TEPEZZA) and pipeline with the objective of maximizing Amgens value proposition.

TEPEZZA (teprotumumab-trbw) is the first and only FDA-approved therapy for Thyroid Eye Disease (TED) a serious progressive and potentially vision-threatening autoimmune condition. TEPEZZA is a fully human monoclonal antibody that targets and inhibits the insulin-like growth factor-1 receptor (IGF-1R) a key driver of TED pathophysiology. By blocking IGF-1R signaling TEPEZZA has been shown to reduce inflammation orbital tissue expansion and proptosis improving both functional and quality-of-life outcomes.

Clinical studies have demonstrated its efficacy and safety across patients with active and chronic lowclinical activity score (CAS) TED highlighting its broad impact on disease management. TEPEZZA represents a transformative advancement for patients with ongoing research exploring its potential in other IGF-1Rmediated conditions.

At Amgen we are deeply committed to advancing innovative therapies for rare diseases where the need is greatest and the impact can be life changing. The development and success of TEPEZZA exemplify this mission underscoring our dedication to bringing breakthrough treatments to patients who have long been underserved

Responsibilities:

• Developing the US medical strategy for teprotumumab through deep understanding of medical practice to maximize access and reimbursement

• Contributing to the product strategy for teprotumumab and TED franchise pipeline

• Developing and leading external stakeholder plan management communication evidence generation and medical education

• Developing and leading execution of a US medical communication strategy including clinical narrative framework scientific platform core content congresses and publications

• Engaging US external stakeholders to strengthen the understanding of the unmet need and medical value of Teprotumumab and TED franchise pipeline

• Elevating Amgens reputation as a science-based and patient focused reliable partner

• Partnering on evidence generation and ensuring key regional/local needs are addressed

• Providing medical insights and advice internally

Win

What we expect of you

We are all different yet we all use our unique contributions to serve patients. The candidate we seek is an experienced leader with the following qualifications.

Basic Qualifications:

• Doctorate degree & 6 years of directly related experience OR

• Masters degree & 10 years of directly related experience OR

• Bachelors degree & 12 years of directly related experience AND

• 6 years of managerial experience directly managing people and/or leadership experience leading teams projects programs or directing the allocation of resources

Preferred Qualifications:

• MD PharmD or PhD degree from an accredited school

• 3 years of Medical Affairs experience in Immunology ophthalmology or pharmacology

• Rare disease knowledge and experience

• 5 or more years of Medical Affairs experience in the biopharmaceutical industry (biotech pharmaceutical or CRO) that includes collaborations with integrated delivery networks accountable care organizations and/or payers

• 5 or more years of Rare Disease experience

• 3 or more years of clinical research experience and/or basic science combined with clinical teaching and patient care activities

• Familiarity with US regulatory organizations guidelines and practices

• Knowledge of Good Clinical Practices (GCP) and US regulations and guidelines

• History of solving problems while exhibiting superior judgment and a balanced realistic understanding of issues

• Knowledge of pharmaceutical product development product lifecycle and commercialization processes including but not limited to clinical operations commercial regulatory and medical affairs

They will also embody the Amgen leadership attributes which are:

• Inspire: Create a connected inclusive and inspiring work environment that empowers talent to thrive

• Accelerate: Enable speed that matches the urgency of patient needs by encouraging progress over perfection

• Integrate: Connect the dots to amplify the collective power of Amgen to drive results for patients staff and shareholders

• Adapt: Lead through change by adapting to an ever-changing environment and defining a clear course of action to deliver results

Thrive

What you can expect of us

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture well support your journey every step of the way.

The annual base salary range for this opportunity in the U.S. is $343334 - $403728.

In addition to the base salary Amgen offers a Total Rewards Plan based on eligibility comprising of health and welfare plans for staff and eligible dependents financial plans with opportunities to save towards retirement or other goals work/life balance and career development opportunities that may include:

• Comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions group medical dental and vision coverage life and disability insurance and flexible spending accounts.

• A discretionary annual bonus program or for field sales representatives a sales-based incentive plan

• Stock-based long-term incentives

• Award-winning time-off plans and bi-annual company-wide shutdowns

• Flexible work models including remote work arrangements where possible

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Salary Range