Biotechnician II

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates we look for scientific and business professionals who are highly motivated collaborative and most importantly share our passionate interest in fighting cancer.

General Description: The Biotechnician II position will directly enable the initial start-up phase of the Hopewell manufacturing facility and then shift focus to hands-on execution and support of cGMP manufacturing operations.

Facility Start-Up: Focused on activities required to design build commission and license BeOnes first biopharmaceutical plant in the United States. Essential functions of the job may include but not limited to:

• Design review
• Equipment selection procurement and testing
• Protocol development and execution
• Acceptance testing and equipment/automation debugging
• Technical training

Hands-On cGMP Operations: Focused on execution of cGMP manufacturing activities required to deliver the production plan reliably and compliantly. Essential functions of the job include but not limited to:

• Follow cGMP procedures to support manufacturing execution and automated recipes
• Media preparation & transfers / filtration
• Cell culture sampling monitoring & transferring
• Harvest operations
• Buffer preparation & transfers / filtration
• Operational and cleaning of chromatography and filtration systems.
• Equipment & process troubleshooting
• Deviation identification reporting drafting investigate closure
• Change control drafting presenting closure
• cGMP procedure development and optimization

• Requesting staging and verifying materials for production activities
• Setup and preparation of equipment for formulation and filling
• Final filtration and formulation of drug product
• Aseptic filling of vials inside a Grade A isolator using automated filling equipment
• Performing in-process visual inspection for quality assurance
• Labeling and packaging of finished drug product in compliance with cGMP
• Completing batch documentation and reviewing records for accuracy
• Supporting routine cleanroom operations equipment sanitization and environmental monitoring
• Assisting in deviation investigations and participating in CAPA implementation as needed

• Operation of Distributed Computer System (DSC)
• Operation of equipments such as Clean-in-Place (CIP) Steam-in-Place (SIP) skid Caustic skid autoclave part washer filter integrity tester biowelders etc.
• Operation of SoloVPE protein concentration analyzer
• Cleaning of the facility
• Collection of samples for environmental monitoring
• Removal of process waste

Qualifications:

• At least 1 year of relative experience required.
• High school education or GED required.
• AS/BS/BA in science related field biopharmaceutical or equivalent technical experience preferred.
• Evidence of good verbal and written communication.
• Ability to work in fast paced dynamic environment with competing priorities.
• Demonstrated ability to collaborate within and between diverse groups.
• Proactive identification and implementation of continuous improvement opportunities.
• Aptitude for learning moderately complex technical systems.
• Able to receive and incorporate feedback passion for ongoing professional development a plus.

Physical Requirements:

• Must be able to stand for long periods up to 8 to 10 hours/day.
• Must be able to reach above shoulder level bend/stoop push/pull and handle/grip frequently.
• Must be able to work scheduled 40 hours with the ability to work overtime as needed.
• Must be comfortable in working in varying temperatures.
• Frequent lifting pushing pulling and carrying. Ability to lift to 40 lbs.
• Regular reaching bending stooping and twisting.
• Repetitive motion and substantial movement of the wrists hands and/or fingers.
• Environment requires dedicated gowns depending on area.
• Work with hazardous materials and chemicals.
• Willing to work any shift.

Computer Skills:

• Familiarity with computer-based systems. Word Excel and PowerPoint a must.

Travel:

• International and domestic periodically.

Global Competencies

When we exhibit our values of Patients First Driving Excellence Bold Ingenuity and Collaborative Spirit through our twelve global competencies below we help get more affordable medicines to more patients around the world.

• Fosters Teamwork
• Provides and Solicits Honest and Actionable Feedback
• Self-Awareness
• Acts Inclusively
• Demonstrates Initiative
• Entrepreneurial Mindset
• Continuous Learning
• Embraces Change
• Results-Oriented
• Analytical Thinking/Data Analysis
• Financial Excellence
• Communicates with Clarity

BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate including but not limited to job-related skills depth of experience certifications relevant education or training and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical Dental Vision 401(k) FSA/HSA Life Insurance Paid Time Off and Wellness.

We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race religion color sex gender identity sexual orientation age disability national origin veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications merit and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973 the Vietnam Era Veterans Readjustment Assistance Act of 1974 Title I of the Americans with Disabilities Act of 1990 and any other applicable federal state or local laws applicants who require reasonable accommodation in the job application process may contact .