Associate Director, Drug Discovery Toxicology
Associate Director, Drug Discovery Toxicology
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Job Description
Your work will change lives. Including your own.
The Impact Youll Make
We are seeking an experienced Drug Discovery Toxicologist who will provide project teams with scientific expertise and leadership for the safety assessment of Recursion programs from early discovery through to candidate selection and beyond. You will contribute to the assessment and selection of novel drug targets and optimisation of novel candidate molecules using innovative molecular cellular and in vivo technologies to maximise predictive safety science and investigative toxicology.
In this role you will:
- Represent Toxicology as the Subject Matter Expert on cross-functional project teams within Discovery
- Provide expert input guidance and strategy on project safety assessments with a specific focus on discovery projects
- Act as a key resource for early safety assessment during the drug discovery phase providing scientific knowledge and expertise to cross-functional project teams
- Use established toxicology screening strategies to predict assess and mitigate target- and drug-related safety risks in support of the drug discovery portfolio
- Refine and implement innovative experimental strategies and use the data to assess and/or provide mechanistic understanding of safety issues
- Collaborate with CROs to ensure best practice for in vitro and/or in vivo safety assessment
- Prepare verbal and written summaries for internal discussions. Work with the Discovery teams to develop optimal strategies to address specific safety issues within the project teams
- Present summary data to project teams Recursion senior leadership and external partners as needed
The Team Youll Join
Reporting to the Head of Toxicology you will have responsibility for the safety assessment of compounds moving through Discovery and into Development. As the Toxicology subject matter expert you will work collaboratively with project team members across functions including pharmacology DMPK and chemistry to support progression of compounds through the portfolio.
The Experience Youll Need
- DVM PharmD PhD in toxicology Pathology Physiology Biochemistry or expertise in related biological scientific disciplines with an emphasis on Oncology/Immunology is preferred. Board Certification in Toxicology (DABT/ERT) is a plus
- 7 years experience in safety sciences in the Biotech/Pharma industry
- Experience in project team membership as a toxicology representative in a matrix environment
- Experience with in silico and in vitro safety assessment is a must; experience with in vivo safety assessment would be an advantage
- An in-depth knowledge of discovery toxicology and experience designing and critically evaluating results of exploratory toxicology studies
- Experience of secondary pharmacology assessment would be an advantage
- An understanding of in vitro to in vivo translation of potential toxicities and implications for human safety
- Broad background in novel methods of identifying potential toxicities and developing risk mitigation plans
- Experience with the use of AI tools to predict toxicology endpoints would be an advantage
- Highly motivated scientist who can work independently with excellent oral/written communication skills
Working Location & Compensation:
This is office-based hybrid role can be based in either ourNew York City or Londonoffice. Employees are expected to work in the office at least 50% of the time. Relocation support can be provided for this role. At Recursion we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role the estimated current annual base range for this role is:
- $182700 - 229900 USD for candidates based in the United States
- 93500 - 109700 GBP for candidates based in the United Kingdom
You will also be eligible for an annual bonus and equity compensation as well as a comprehensive benefits package.
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The Values We Hope You Share:
- We act boldly with integrity. We are unconstrained in our thinking take calculated risks and push boundaries but never at the expense of ethics science or trust.
- We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up speaking honestly and taking action.
- We learn actively and adapt rapidly. Progress comes from doing. We experiment test and refine embracing iteration over perfection.
- We move with urgency because patients are waiting. Speed isnt about rushing but about moving the needle every day.
- We take ownership and accountability. Through ownership and accountability we enable trust and autonomyleaders take accountability for decisive action and teams own outcomes together.
- We are One Recursion. True cross-functional collaboration is about trust clarity humility and impact. Through sharing we can be greater than the sum of our individual capabilities.
Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate support one another spend our time make decisions and celebrate collectively.
More About Recursion
Recursion (NASDAQ: RXRX) is a clinical stage TechBio company leading the space by decoding biology to radically improve lives. Enabling its mission is the Recursion OS a platform built across diverse technologies that continuously generate one of the worlds largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale up to millions of wet lab experiments weekly and massive computational scale owning and operating one of the most powerful supercomputers in the world Recursion is uniting technology biology and chemistry to advance the future of medicine.
Recursion is headquartered in Salt Lake City where it is a founding member of BioHive the Utah life sciences industry collective. Recursion also has offices in Toronto Montral New York London Oxford area and the San Francisco Bay area. Learn more at or connect onX (formerly Twitter)andLinkedIn.
Recursion is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity national origin age disability veteran status or any other characteristic protected under applicable federal state local or provincial human rights legislation.
Accommodations are available on request for candidates taking part in all aspects of the selection process.
Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursions internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
Required Experience:
Director
Employment Type
Full Time
