Sr. Manager Downstream Operations, mAb products
Sr. Manager Downstream Operations, mAb products
Employer Active
Job Alert
You will be updated with latest job alerts via email
Share
Job Alert
You will be updated with latest job alerts via email
Job Description
Use Your Power for Purpose
Our breakthroughs would not make it to the hands of patients without our dedicated and agile pharmaceutical manufacturing team. We rely on members who understand the importance and impact of their role in Pfizers mission. Patients need colleagues like you who take pride in their work and always strive to improve outcomes. You will help ensure that patients and physicians have the medicines they need when they need them. Your role is crucial in making sure our innovations reach those who need them most. By being part of our team you contribute to a mission that values dedication and agility ensuring that every patient receives the best possible care.
What You Will Achieve
The Sr. Manager Downstream Operations is responsible for managing mAb production through multiple layers of a cGMP manufacturing operation that emphasizes safety right the first-time manufacturing and the All In culture while ensuring compliance with Standard Operating Procedures (SOPs) current Good Manufacturing Practice regulations (cGMP) product licenses corporate policies and safety practices. The Sr. Manager Downstream Operations is expected to have an organization-wide perspective for all programs involving his/her functional area and to set priorities accordingly based on overall Company and departmental goals.
In this role you will:
Strategic Leadership
Set and manage objectives for multiple complex projects.
Influence senior management and align initiatives with divisional strategy.
Champion innovation and knowledge sharing across functions.
IMEX & Ecosystem Integration
Collaborate with Process Centric Teams to meet global lean manufacturing standards.
Financial & Facilities Management
Develop and manage budgets for labor materials and capital.
Plan for short- and long-term equipment needs and support network-wide systems.
Compliance & Quality
Ensure regulatory compliance and manage deviation investigations.
Oversee SOP development and quality assurance processes.
Manage performance staffing and career development.
Organizational & People Leadership
Lead and develop a team of leaders and production staff.
Promote a positive feedback-rich culture aligned with the Sanford All In values.
Operational Oversight
Guide manufacturing and technology teams in compliance audit readiness and equipment lifecycle.
Oversee production operations ensuring adherence to cGMP and safety standards.
Lead continuous improvement initiatives using LEAN and Six Sigma.
Here Is What You Need (Minimum Requirements)
BA/BS with at least 6 years of experience or MBA/MS with at least 5 years of experience or PhD/JD with at least 1 year of experience or MD/DVM with any years of experience
Strong background in supervision or management roles within the pharmaceutical industry
Proficiency in Lean and Six Sigma tools
Robust people management skills
Proactive approach in engaging with key stakeholders
Experience in managing complex projects and leading cross-functional teams
Excellent problem-solving and decision-making skills
Bonus Points If You Have (Preferred Requirements):
Advanced degree (Masters PhD JD MD DVM) in a relevant field
Experience in talent management and development
Strong communication and interpersonal skills
Ability to drive innovation and manage change
Experience in budget planning and financial management
Knowledge of Good Manufacturing Practices (GMP) and regulatory compliance
Ability to manage Pfizer direct reports effectively
Strong leadership and team-building skills
Experience in strategic planning and execution
Experience in problem-solving negotiations presentation and supervision of a multi-layered organization.
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers develop and coach others oversee and guide the work of other colleagues to achieve meaningful outcomes to create business impact.
PHYSICAL/MENTAL REQUIREMENTS
Ability to stand for 1 hour at a time sit for 2 to 3 hours at a time walk long distances and bend to obtain items from lower shelving/cabinets.
NON-STANDARD WORK SCHEDULE TRAVEL OR ENVIRONMENT REQUIREMENTS
Position supports a 24/7 manufacturing operation. Some overtime may be required including some infrequent weekend work. Some travel may be required on an infrequent basis as well. Aseptic gowning will be required on the manufacturing floor.
Other Job Details:
Last day to Apply: August 5th 2025
Work Location Assignment:Onsite
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care providers name address and the type of payments or other value received generally for public disclosure. Subject to further legal review and statutory or regulatory clarification which Pfizer intends to pursue reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse your name address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race color religion sex sexual orientation age gender identity or gender expression national origin disability or veteran status. Pfizer also complies with all applicable national state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Required Experience:
Manager
Employment Type
Full-Time
