Senior Backend Engineer (AI Focus) - Atrix

At Atrix AI we believe life sciences teams deserve more than just datathey deserve answers.

Medical affairs and commercial teams sit on mountains of messy unstructured information that could impact patient outcomes if only they could make sense of it. Atrix is helping the worlds most innovative companies in pharma and medtech turn AI into a trusted ally for clinical decision-making.

Were on a mission to make AI-native workflows that are fast intuitive and impactfulwithout compromising on compliance privacy elegance or trust. Were backed by top-tier venture capital firms in San Francisco and New York giving us the support to move quickly and build ambitiously.

Were a small focused team working fast listening to customers and shipping quickly. If you love building beautiful products translating real-world complexity into intuitive UX and want your code to power decisions that improve lives youll thrive here.

The Role Description

Youll be a core builder of Atrixs backend infrastructure powering AI-native workflows that ingest unstructured data structure it with AI and deliver insights that matterinstantly and reliably.

Youll work on scalable data pipelines robust APIs and real-time inference systems supporting everything from complex agent workflows to customer-facing dashboards. Whether its building retrieval pipelines optimizing async background workers or designing clean secure APIs your work will be foundational to how our platform works and scales.

Were building a modular agentic platform that connects to customer-approved data sources transforms unstructured data using LLM-based agents and delivers decision-ready intelligence to regulated teams.

Youll tackle rich backend engineering challenges like:

• System Design & Reliability Scale to handle massive amounts of records with fast response times

• LLM Ops Make AI outputs explainable auditable and efficient

• Multi-Tenant Infra Isolate customer data across parallelized pipelines

• AI Performance Tuning Optimize inference cost caching and latency

• RAG Pipelines & Contextual Workflows Connect structured unstructured data for real-world usage

Youll work closely with the Engineering Lead and CEO and collaborate across product AI and GTM. As one of our earliest backend engineers youll influence everything from our architecture to hiring bar.

This is an in-person role based in NYC with flexibility for remote work on some days as needed.

Responsibilities

This role is perfect for someone who thrives on solving deep technical problems loves optimizing systems for speed and scale and gets energized by seeing their work used in real-world high-stakes environments. If youre excited about powering AI workflows behind the scenesand building infrastructure thats as elegant as it is reliablewed love to talk.

In this role you will:

• Design and own major modules of our backend architecture (APIs workers orchestration)

• Optimize performance and reliability of data processing and AI inference systems

• Build and maintain LLM-powered backend features and multi-step workflows

• Collaborate with product and AI teams to launch performant production-grade AI features

• Improve observability traceability and modularity of backend systems

• Lead customer-focused feature delivery with high attention to security and compliance

Must haves

• 5 years backend engineering experience in fast-paced product teams

• 2 years of Python experience including async programming

• Expertise with one or more frameworks: FastAPI Flask Django

• Strong experience with SQL (PostgreSQL) and ORMs (SQLAlchemy or equivalent)

• Experience building APIs background workers and distributed systems

• Understanding of how LLMs embeddings or RAG workflows function

• Startup experience or demonstrated ownership in complex backend projects

Nice to haves

• Familiarity with Celery LangChain LlamaIndex or other LLM orchestration tools

• Exposure to RAG or context injection workflows

• Experience with AWS Terraform Kafka or PyTorch

• Background in healthcare data security or regulated environments

Why Join Atrix as a Backend Engineer

Mission-Driven Impact
Your code will help life sciences teams deliver better treatmentsfaster. Every system you build supports real-world clinical outcomes.

Real AI Real Stakes
This isnt research tooling. Youll make AI work for real customersensuring reliability explainability and speed in high-stakes environments.

Deep Backend Ownership
Shape architecture modular services and engineering culture from day one.

Scale Complexity
Youll design systems that operate on thousands of records across multi-client multi-agent environmentswith LLMs at the core.

Early Team High Growth
Be part of a tight-knit mission-oriented team and grow into our Backend Lead Engineer as we scale.

What We Offer

• Compensation: Competitive salary equity package

• Health & wellness support Stipend medical (vision dental health) insurance coverage

• Unlimited PTO Recharge when you need to

• High learning velocity Get exposed to AI infra GTM and real customers daily

Required Experience:

Senior IC