Executive Medical Director, Cardiovascular-Kidney-Metabolic

Career Category

Job Description

JOIN AMGENS MISSION OF SERVING PATIENTS

At Amgen if you feel like youre part of something bigger its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.

Since 1980 weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology Inflammation General Medicine and Rare Disease we reach millions of patients each year.

As a member of the Amgen team youll help make a lasting impact on the lives of patients as we research manufacture and deliver innovative medicines to help people live longer fuller happier lives.

Our award-winning culture is collaborative innovative and science based. If you have a passion for challenges and the opportunities that lay within them youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Executive Medical Director Cardiovascular-Kidney-Metabolic (CKM)

Live

What you will do

Lets do this. Lets change the world. The Obesity organization is seeking an Executive Medical Director that will oversee a team of physician-scientists that support evidence generation for cardiovascular risk reduction in the metabolic space.

This role will focus on heart failure and you will oversee a heart failure outcomes trial with MariTide a novel bispecific monoclonal antibody-peptide conjugate being investigated for the treatment of obesity and related conditions.

Responsibilities:

• Provide clinical/scientific knowledge into the development design delivery and communication of the global evidence generation plan for multiple metabolic assets.

• Support cross-functional and global collaborations to integrate broad medical scientific and commercial input into the development program

• Participate and provide clinical input into safety and regulatory interactions

• Interpret and communicate clinical trial data

• Oversee the authoring of clinical study reports publications and regulatory submissions

• Develop relationships with key opinion leaders and make scientific presentation at advisory boards key scientific meetings and external committee meetings as delegated by Global Development Lead

• Provide clinical content input to materials to be used in Scientific Affairs as well as the Commercial Organization

• Contribute to TPP (target product profile) and Global Product Safety (GPS) development

• Create development options and present to Global Dev Review Committee (GDRC) Obesity Leadership Team (OLT)

• Interact with TA leadership and extended team to develop strategies options

• Interact with Center for Design Analysis (CfDA) Center for Observational Research (CfOR) Clinical Pharmacology Modeling & Simulation (CPMS) etc. to bring innovative later development options.

Win

What we expect of you

We are all different yet we all use our unique contributions to serve patients. The candidate we seek is an experienced leader with the following qualifications.

Basic Qualifications:

• MD or DO degree from an accredited medical school AND

• 5 years of industry or academic research experience AND

• 6 years of managerial experience directly managing people and/or leadership experience leading teams projects programs or directing the allocation of resources

Preferred Qualifications:

• Five (5) or more years of clinical research experience in the biopharmaceutical industry (biotech pharmaceutical or CRO company) in cardiovascular outcomes evidence generation.

• Eight (8) or more years of clinical research experience and/or basic science research combined with clinical teaching and patient care activities

• Oversee late phase evidence generation from Phase 2 and beyond by leading the design and implementation of the Total Evidence Generation Plan (EGP) including registrational non-registrational and real-world evidence

• Previous experience in regulatory interactions and filing activities for Cardiovascular indications

• Experience with developing study concepts for clinical development and clinical trial designs with cross functional input including biostatistics observational research and patient reported outcomes in Phase 1 2 and/or 3 clinical trials in obesity or diabetes

• Strong and versatile clinical development experience in cardiovascular disease endocrinology and accreditation in relevant sub-specialty

• Knowledge of pharmaceutical product development product lifecycle and commercialization processes

• Knowledge of Good Clinical Practices (GCP) FDA and EMEA/CHMP regulations and guidelines and applicable international regulatory requirements

• Leadership experience/potential as a medical expert in a complex matrix environment

• Ability to effectively present ideas and document complex medical/clinical concepts in both written and oral communication

• Strong interpersonal skills and problem-solving abilities while exhibiting superior judgment and a balanced realistic understanding of issues and resolution path

They will also embody the Amgen leadership attributes which are:

• Inspire: Create a connected inclusive and inspiring work environment that empowers talent to thrive

• Accelerate: Enable speed that matches the urgency of patient needs by encouraging progress over perfection

• Integrate: Connect the dots to amplify the collective power of Amgen to drive results for patients staff and shareholders

• Adapt: Lead through change by adapting to an ever-changing environment and defining a clear course of action to deliver results

Thrive

What you can expect of us

As we work to develop treatments that take care of others we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture well support your journey every step of the way.

The annual base salary range for this opportunity in the U.S. is $343334 - $403278.

In addition to the base salary Amgen offers a Total Rewards Plan based on eligibility comprising of health and welfare plans for staff and eligible dependents financial plans with opportunities to save towards retirement or other goals work/life balance and career development opportunities that may include:

• Comprehensive employee benefits package including a Retirement and Savings Plan with generous company contributions group medical dental and vision coverage life and disability insurance and flexible spending accounts.

• A discretionary annual bonus program or for field sales representatives a sales-based incentive plan

• Stock-based long-term incentives

• Award-winning time-off plans and bi-annual company-wide shutdowns

• Flexible work models including remote work arrangements where possible

As an organization dedicated to improving the quality of life for people around the world Amgen fosters an inclusive environment of diverse ethical committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race color religion sex sexual orientation gender identity national origin protected veteran status disability status or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process to perform essential job functions and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Salary Range