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Job Title:
Associate Scientist I Molecular and Cell Biology
Location:
La Jolla California
Position type:
FLSA:
Research
Exempt
Department:
Technical Development
Finance ID:
Profoundly Improve Peoples lives by Revolutionizing the Delivery of RNA Therapeutics
At Avidity Biosciences we are passionate about the impact of every employee in realizing our vision of improving peoples lives by delivering a new class of RNA therapeutics. Avidity is revolutionizing the field of RNA with its proprietary AOCs which are designed to combine the specificity of monoclonal antibodies with the precision of oligonucleotide therapies to address targets and diseases previously unreachable with existing RNA therapies. If you are a committed solution-oriented thinker join us in making a difference and become part of our growing culture that is integrated collaborative agile and focused on the needs of patients.
Avidity Biosciences Inc.s mission is to profoundly improve peoples lives by delivering a new class of RNA therapeutics - Antibody Oligonucleotide Conjugates (AOCs). Utilizing its proprietary AOC platform Avidity demonstrated the first-ever successful targeted delivery of RNA into muscle and is leading the field with clinical development programs for three rare muscle diseases: myotonic dystrophy type 1 (DM1) Duchenne muscular dystrophy (DMD) and facioscapulohumeral muscular dystrophy (FSHD). Avidity is broadening the reach of AOCs with its advancing and expanding pipeline including programs in cardiology and immunology through internal discovery efforts and key partnerships. Avidity is headquartered inSan Diego CA.For more information about our AOC platform clinical development pipeline and people please visit and engage with us on LinkedIn and X.
The Opportunity
As Avidity transitions from late stage clinical to commercial operations an effective quality control strategy will be critical to ensuring the safety efficacy and reproducibility of our drug products. To facilitate these efforts we are seeking an Associate Scientist I to join the Analytics group with experience in developing and optimizing robust cell-based assays for later phase clinical programs. The position will also support preclinical development of second-generation AOC therapeutics. This is a unique opportunity and will enable the individual to interact with multiple departments including Chemistry Biology and Bioanalytical Sciences. This individual will work in a high-paced matrix environment and must be able to communicate and collaborate between them effectively.
What You Will Contribute
Excellent laboratory techniques and the ability to work independently
Significant experience with mammalian cell culture and cell line development
Proficiency with in vitro transfection dosing and downstream assays
Experience with running ELISA workflows and assistance with creation of new ELISA methods
Wet-bench efforts towards analytical assay execution and validation
Maintain up to date ELN
Ability to communicate data findings and next steps to a team with a broad background
Some prior experience with assay automation
Ability to design and build DNA plasmids and use related software such as Benchling molecular biology suite and/or SNAP gene
Flow-cytometry experience
A positive can-do attitude; someone that thrives working as a part of a highly productive team
What We Seek
BA or BS in biology or related discipline with 8 years of work experience in biotechnology or a university setting laboratory or an BA/MS degree in biology bioengineering cell biology or equivalent with 6 years of industry experience
Experience with analytical assay development and qualification
Proven ability to thrive and enable success in a cross-functional and collaborative environment.
Excellent communication and interpersonal skills and the ability to facilitate constructive and expedient problem-solving.
Ability to multi-task manage conflict and work efficiently in a fast-paced environment.
R or python-based data wrangling skills to facilitate data analysis workflows (preferred but not required)
What We Will Provide to You
The base salary range for this role is $99750 $110000. The final compensation will be commensurate with such factors as relevant experience skillset internal equity and market factors.
Avidity offers competitive compensation and benefits which include the opportunity for annual and spot bonuses stock options and RSUs as well as a 401(k) with an employer match. In addition the comprehensive wellness program includes coverage for medical dental vision and LTD and four weeks of time off.
A commitment to learning and development which includes a variety of programming internally developed by and for Avidity employees opportunities for job-specific training offered by industry and an education reimbursement program.
Avidity Biosciences
10578 Science Center Dr. Suite 125
San Diego CA
92121
O:
F:
Required Experience:
IC
Full-Time