Job description: This position will play a key role in the development of complex in vitro models to support late-stage internal programs. The ideal candidate will have extensive experience with primary cell culture and complex in vitro models and the potential of applying these models to advance drug discovery programs. The applicant should be a creative research driven scientist interested in combining a knowledge of autoimmune disease with complex in vitro models to advance drug discovery.
Responsibilities: - Responsible for the development of complex in vitro models that mimic the pathophysiology of immune mediated diseases with a focus on Skin autoimmunity.
- Identify internalize develop and optimize new methods and technologies to deliver in vitro models of Skin autoimmune diseases using commercial and custom Skin on a chip micro physiological system.
- Utilize complex in vitro models to drive the advancement of Client therapeutics and combinations.
- Identify and solve technical problems independently conceive and implement Client experimental approaches.
- Generate data in a timely manner and effectively communicate results internally across departments and at internal and external scientific conferences; may author or co-author peer-reviewed scientific papers or patents.
- Effectively and accurately record experimental results.
- A strong team player in a cross functional collaborative environment thriving for world class excellence and maintains strong working relationships with internal global and external collaborators.
Requirements: - Bachelors Degree or equivalent education and typically 8 years of experience masters degree or equivalent education and typically 6 years of experience or PhD and typically 0 years of experience.
- Extensive experience with primary cell cultures and in vitro cell based assays is required.
- Experience specifically with primary keratinocytes organoids dermal fibroblasts and human immune cells is preferred.
- Experience in complex in vitro models (i.e. spheroids organoids organ-on-a-chip microfluidics) is preferred.
- Experience with disease modelling using primary cells and microphysiological systems a plus.
- Experience with imaging technologies.
- Project management experience preferred.
- Ability to build relationships and work collaboratively with cross-functional teams in a highly matrixed organization.
- Established history of publications in peer-reviewed journals and presentations at scientific conferences.
- Able to work both independently and as part of a team when required.
- Demonstrate excellent communication skills and specifically illustrate strong oral and written technical communications.
- Demonstrated problem-solving skills and capability to overcome complex issues.