Head of Pharmacokinetics and Pharmacodynamics -M/F/D
Head of Pharmacokinetics and Pharmacodynamics -M/F/D
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Job Description
Who we are
Pierre Fabre is the 2nd largest dermo-cosmetics laboratory in the world the 2nd largest private French pharmaceutical group and the market leader in France for products sold over the counter in pharmacies.
Its portfolio includes several medical franchises and international brands including Pierre Fabre Oncologie Pierre Fabre Dermatologie Eau Thermale Avne Klorane Ducray Ren Furterer A-Derma Naturactive Pierre Fabre Oral Care.
Established in the Occitanie region since its creation and manufacturing over 95% of its products in France the Group employs some 10000 people worldwide. Its products are distributed in about 130 countries.86% of the Pierre Fabre Group is held by the Pierre Fabre Foundation a government-recognized public-interest foundation while a smaller share is owned by its employees via an employee stock ownership plan.
In 2019 Ecocert Environment assessed the Groups corporate social and environmental responsibility approach in accordance with the ISO 26000 sustainable development standard and awarded it the Excellence level.
Pierre Fabre is recognized as one of the Worlds Best Employers 2021 by Forbes. Our group is ranked in the Top 3 in the cosmetics industry and in the Top 10 in the pharmaceutical industry worldwide.
Your mission
We are looking for a Pharmacokinetics/Pharmacodynamics Group Leader to lead a team of 6 professionals including PKPD project leaders Modeling and Simulation experts and Clinical Pharmacology specialists.
The team is responsible for early DMPK and PK/PD studies of both small and large molecules as well as clinical pharmacology across all phases of clinical development.
In this role you will guide the group in strategy and functional expertise establish a cohesive PBPK-based modeling approach mentor your team and oversee their training and development. You will also work closely with internal experts in data science oncology rare diseases toxicology and biomarkers to ensure a unified project strategy.
Key Responsibilities:
Lead coach and develop a team of experts in pharmacokinetics pharmacodynamics and clinical pharmacology.
Provide expert guidance in developing comprehensive DMPK PK/PD and regulatory strategies from target validation through post-registration stages.
Collaborate with internal stakeholders including specialists in data science oncology rare diseases toxicology and biomarkers to ensure alignment and coherence in project strategies.
Oversee the groups activities and ensure the continuous professional growth and development of your team.
Foster a culture of generosity focusing on supporting and enabling the success of others creating an environment where your team feels motivated to contribute their best.
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Pierre Fabre recrute en CDI un Responsable du Dpartement pharmacocintique / pharmacodynamique pour manager une quipe de 6 chefs de projet PKPD experts en modlisation et simulation et spcialistes en pharmacologie clinique.
Lquipe est responsable des premires tudes DMPK et PK/PD de petites et grosses molcules ainsi que de la pharmacologie clinique toutes les phases de dveloppement. Dans ce rle vous construirez la stratgie tablirez une approche cohrente de modlisation base sur le PBPK encadrerez votre quipe et superviserez leur formation et leur dveloppement. Vous travaillerez galement en troite collaboration avec des experts internes en Data Science en oncologie en maladies rares en toxicologie et en biomarqueurs afin de garantir une stratgie de projet unifie.
Who you are
Required Qualifications:
- At least 10 years of experience in scientific research within the pharmaceutical industry specifically in areas related to PK/PD/ADME science.
- Expertise in modeling and simulation approaches.
- Strong experience in either early-stage small molecule discovery or Clinical Pharmacology.
- Experience in leveraging ADME and PK/PD science to address efficacy and safety questions related to human exposure and influence project strategies advise on therapeutic dosing design and candidate selection guide drug discovery strategy and implement adequate de-risking plans.
- Demonstrated leadership skills with experience managing teams and individuals.
- Strong expertise in regulatory submissions to health authorities.
Preferred Qualifications:
- Experience in the fields of oncology and/or rare diseases.
- Advanced skills in data analysis and biomarker development.
Une exprience de 10 ans min dans la recherche scientifique au sein de lindustrie pharmaceutique en particulier en pharmacocintique pharmacodynamique et ADME.
- Expertise en modlisation et simulation.
- Solide exprience dans les approches pour petites molcules phase prcoce ou en clinique.
- Exprience de lutilisation des sciences ADME et PK/PD pour rpondre aux questions defficacit et de scurit chez lhomme.
- Solide expertise en matire de soumissions rglementaires aux autorits de sant.
We are convinced that diversity is a source of fulfillment social balance and complementarity for our employees which is why our offers are open to all without restriction.
Required Experience:
Director
Employment Type
Full-Time
