PAT Scientist III
PAT Scientist III
Employer Active
Job Alert
You will be updated with latest job alerts via email
Share
Job Alert
You will be updated with latest job alerts via email
Not Disclosed
Salary Not Disclosed
1 Vacancy
Job Description
Work Schedule
Standard (Mon-Fri)Environmental Conditions
Adherence to all Good Manufacturing Practices (GMP) Safety Standards Laboratory Setting Loud Noises (Equipment/Machinery) Office Some degree of PPE (Personal Protective Equipment) required (safety glasses gowning gloves lab coat ear plugs etc.)Job Description
As a Manufacturing Scientist you will contribute to the development validation and optimization of chemometric models for oral solid dosage (OSD) products specifically in our Continuous Manufacturing line. The ideal candidate brings expertise in Chemometrics multivariate data analysis and programming skills (Python R and/or MATLAB) to support model-based control real-time monitoring and data-driven decisions. You will collaborate with multi-functional teams and clients to improve process performance and ensure model lifecycle adaptability. Experience in process modeling and/or OSI PI is a plus.
What will you do
Support the development deployment and lifecycle management of Process Analytical Technology (PAT) tools and multivariate models used in continuous manufacturing.
Apply chemometric techniques (e.g. PCA PLS) to develop validate and maintain predictive and/or classification models for process monitoring and control.
Analyze process and spectral data to support investigations trend analysis and performance supervising across product lifecycle stages.
Collaborate with operations quality engineering and analytical teams to ensure robust process control and monitoring.
Serve as the technical lead on client-facing projects and provide scientific justifications for model performance control strategies and data use.
Author protocols reports and documentation aligned with GMP and regulatory requirements.
Support the integration of process data infrastructure visualization and analytics tools (e.g. dashboards) into manufacturing workflows.
Provide day-to-day technical support for commercial CM processes and act as scientific owner for assigned products.
Education
Bachelors degree in Chemical Engineering Pharmaceutical Sciences Chemistry Data Science or a related field is required. A Masters or Ph.D. with a focus on Chemometrics process systems engineering or data analytics is preferred.
Experience
Minimum of 5 years proven experience with a Bachelors degree
Minimum of 2 years with a Masters degree
No prior experience required with a Ph.D. if coursework and research align with Chemometrics continuous manufacturing or process modeling
Hands-on experience with continuous manufacturing PAT model development and spectroscopy techniques (e.g. NIR Raman)
Knowledge Skills Abilities
Proficiency in programming language for data analysis modeling and visualization
Proven understanding of multivariate statistical analysis data preprocessing and validation methods
Familiarity with GMP FDA/EMA guidelines and ICH standards related to PAT and model validation
Experience with process control model monitoring or data integrity frameworks preferred
Excellent communication and problem-solving skills with the ability to lead multi-functional discussions
Organized dedicated and able to prioritize in a fast-paced environment
Physical Requirements
Position requires standard mobility and coordination to navigate office and manufacturing spaces; ability to stand walk kneel and occasionally lift items between 1035 pounds. Prolonged keyboard and screen use may be required.
Join Us
At Thermo Fisher Scientific your technical skills will directly support ground breaking continuous manufacturing initiatives. Help us drive innovation and deliver high-quality medicines faster and more efficiently.
Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate
Employment Type
Full-Time
