Job Title: Senior Scientist
Location: San Diego CA
Employment Type: Direct Hire
Salary: $140000 - $160000 annually
Job Summary:
Our client has engaged us in its efforts to recruit a talented and experienced Synthetic Organic and/or Process Development R&D Chemist. The candidate will spearhead chemical reaction discovery and chemical process development to convert biologically-derived intermediates into sustainable industrial chemical products. The candidate will need to perform both in lab experiments and detailed dry-lab planning.
KEY RESPONSIBILITIES:
- Design and demonstrate novel multistep chemical syntheses to produce target compounds.
- Perform discovery reactions with full characterization of all byproducts to quantify reaction performance.
- Implement HPLC GC MS TGA and other relevant analytical techniques to determine reaction products and byproducts.
- Perform reaction optimization DBTL cycles to optimize: conversion yield solvent selection operating conditions and product recovery.
- Identify and apply heterogeneous catalysts for diverse reactions.
- Identify appropriate equipment needed to expand R&D and Pilot Lab Chemistry footprint.
- Perform heterogeneous hydrogenation and hydrodeoxygenation reaction discovery and process development.
- Identify and evaluate appropriate industrial protection groups amendable to massive-scale production.
- Perform aromatic modification reaction discovery and development.
- Evaluate and implement chemical process product purification techniques including crystallization liquid-liquid extraction precipitation filtration and distillation.
- Scale product recovery techniques to Pilot Lab unit operations.
- Leverage knowledge of organic chemistry to design multistep synthetic routes that maintain carbon skeletons and stabilize molecules.
- Apply knowledge of both batch and flow chemistry to develop novel reactions and optimize conditions.
- Lead interactions with CROs in parallel with in-house experiments to rapidly develop chemical processes and to gather additional analytical datasets.
- Exemplify excellence in lab safety and chemical hygiene practices.
- Strengthen and expand both chemistry data and project management to streamline communication in R&D team.
- Organize present and share data challenges questions and strategies with global team.
QUALIFICATIONS:
- Minimum Bachelors Degree in Chemistry or equivalent area from an accredited university. Masters or PhD Degree preferred.
- Experience performing research discovery work to develop multi-step enzymatic synthesis.
- Experience optimizing yield reaction time selectivity conversion and solvent selection for chemical reactions.
- Experience with heterogeneous catalyst and product recovery.
- Experience with hydrogenation deoxygenation protection/deprotection and ring-rearrangement chemistry.
- Experience transferring/scaling multi-step synthesis to pilot scale.
- Experience development analytical methods on GC HPLC MS and/or TGA.
- Experience developing product isolation/purification/crystallization/extraction methods.
- Experiencing implementing organizing and executing project management strategies for communication and transfer of chemistry data and reaction conditions.
- Additional experience to support key responsibilities above.
WORKING CONDITIONS:
- Able to work 5 days a week onsite.
- Able to work in a BSL1 laboratory with hazardous materials including flammables corrosives and general health hazards.
- Able to travel for work 0 - 10.
Scientists,Chemists,Industrial Chemicals,Reaction Engineering