Student Research Assistant (HiWi) in Cancer Immunotherapy â Department of Medicine 2, Hematology and Oncology
Student Research Assistant (HiWi) in Cancer Immunotherapy â Department of Medicine 2, Hematology and Oncology
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Job Description
TheDepartment of Medicine 2 Hematology/ Oncologyat theGoethe UniversityHospital Frankfurtoffers the entire spectrum of diagnostics and therapy of malignant diseases as well as a research program focusing on several cancer entities. The research laboratory of Professor Thomas Oellerich is part of the Frankfurt Cancer Institute and focuses on oncogenic signaling and therapy resistance mechanisms in lymphoma and acute myeloid leukemia.
The lab is furthermore funded by the German Cancer Consortium (DKTK) which was founded in 2012 as one of the six German Centers of Excellence for Health Research (DZG). DKTK aims at bringing promising results from cancer research faster into clinical development and patient care. In the DKTK more than 20 academic research institutions and university hospitals at seven partner sites cooperate with each other and the German Cancer Research Center (DKFZ) in Heidelberg as the core center. ( Role:
You will support day-to-day wet-lab operations with a focus on molecular cloning production of AAV vectors and maintenance of mammalian cell lines.
The project focuses on developing targeted AAV vectors to enhance the efficacy of CAR T cell therapy against aggressive lymphomas. By integrating the latest advances in vector engineering immunotherapy and gene delivery the research aims to significantly improve therapeutic outcomes. This work combines cutting-edge technologies to push the boundaries of next-generation cancer treatments.
- Construct plasmids (restriction/ligation PCR bacterial transformation)
- Perform transfections (chemical/electroporation) and basic viability or reporter assays
- Maintain passage and cryopreserve adherent and suspension cell cultures under sterile conditions
- Produce and titer viral vectors (e.g. lentivirus AAV
- Transduction & FACS analysis with the vector stocks
- Enrolled in a university program (bachelor or master) in biology biochemistry or a related discipline
- Enthusiasm and fascination for biomedical research oncology cell and molecular biology
- High motivation for experimental lab work
- Experiences in cell and molecular biology as well as biochemical lab techniques might be of advantage
- Ability to work in a team sense of responsibility and proactivity
- Basic knowledge in MS-Office (Word Excel)
- Fluent in English
- Due to legal regulations valid proof of measles immunity / measles vaccination is required
- Collective labour agreement TV GU
- International and cosmopolitan working environment
- Contract for at least 1 year
- Flexible working hours in line with your studies
- Scientific education including the management of scientific literature a bi-weekly journal club good scientific presentation and publication practice
- Uniklinik-Campus Mensa Cafs
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Contact: Dr. Niklas Dienstbier (Team Lead - Mechanistic Lymphoma Research)
Phone or Email: 0or
Application Deadline: 10.07.2025
We welcome applications from candidates of all genders. Women are currently underrepresented in these positions at Universittsmedizin Frankfurt. Therefore applications from women are especially encouraged. Applicants with severe disabilities will be given preferential consideration in cases of equal personal and professional qualifications.
Employment Type
Part-Time
