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About Guardant Health
Guardant Health is a leading precision oncology company on a mission to conquer cancer through data. We develop innovative digital and data-driven solutions that empower clinicians and patients across the continuum of cancer care. Our software and platform engineering teams are foundational to enabling seamless integration of our genomic testing with healthcare providers hospital systems and laboratory partners around the country.
About the Role
We are seeking a Manager Software Engineering to lead a highly collaborative team focused on clinical data integrations EMR connectivity and partnerships with hospital networks and reference labs. This is a Palo Altobased leadership role that combines technical depth team management and stakeholder engagementboth internal and external.
Youll be responsible for building and scaling cloud-native integration platforms primarily using Java MuleSoft and AWS to ensure Guardants digital infrastructure enables seamless interoperability with Epic OncoEMR hospital systems and third-party labs. This role is critical to driving clinical adoption operational efficiency and data reliability across Guardants enterprise offerings.
Key Responsibilities
Team & Project Leadership
Lead and mentor a team of backend and integration engineers focused on data exchange between Guardant and external clinical systems.
Oversee delivery of EMR integrations including Epic OncoEMR and other hospital EHR platforms.
Drive development of scalable services and APIs that enable lab partnerships and external data connectivity.
Architecture & Execution
Architect and scale MuleSoft-based integration flows and microservices that manage clinical and lab data pipelines.
Ensure solutions are cloud-native deployed on AWS/Kubernetes and align with Guardants data security compliance and observability standards.
Drive cross-functional initiatives by collaborating with Product Clinical Commercial and Compliance teams.
External Stakeholder Engagement
Serve as a technical point of contact for reference labs hospital networks and third-party integration partners.
Work closely with external IT and data teams to define interface requirements manage onboarding and troubleshoot connectivity issues.
Represent the engineering organization in strategic partner discussions ensuring technical feasibility and long-term scalability.
Operational & Engineering Excellence
Champion engineering best practices including CI/CD test automation observability and resiliency.
Monitor integration KPIs and operational metrics to ensure ongoing reliability and performance of partner-facing systems.
Collaborate with peer leaders across Palo Alto and India to ensure delivery alignment and team health.
Qualifications :
10 years of software engineering experience with at least 3 years in a people management role ideally leading backend or integration-focused teams.
Deep experience with Java (Spring Boot) and MuleSoft in a production environment.
Proven success with cloud-native development on AWS and Kubernetes.
Experience delivering and maintaining integrations with EMRs (Epic OncoEMR) hospital systems or labs.
Strong communication skills including the ability to engage with external technical partners and cross-functional internal teams.
Demonstrated ability to manage complex stakeholder needs prioritize work across multiple initiatives and deliver in a regulated environment.
Nice to Have
Experience in Life Sciences Diagnostics or Healthcare IT.
Familiarity with HL7 FHIR and other healthcare interoperability standards.
Experience working with Laboratory Information Management Systems (LIMS).
Background in regulated environments including HIPAA CAP/CLIA or FDA guidelines.
Why Join Us
At Guardant Health your work enables faster and more effective cancer care. As an Engineering Manager youll shape the integration layer that connects our genomic insights to real-world clinical systems powering decisions that save lives. If youre passionate about scalable architecture partner engagement and engineering for impactwe want to hear from you.
Additional Information :
Hybrid Work Model: At Guardant Health we have defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays Tuesdays and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.
For positions based in Palo Alto CA or Redwood City CA the base salary range for this full-time position is $182500 to $250950. The range does not include benefits and if applicable bonus commission or equity.
Within the range individual pay is determined by work location and additional factors including but not limited to job-related skills experience and relevant education or training. If you are selected to move forward the recruiting team will provide details specific to the factors above.
Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however there may be exposure to high noise levels fumes and biohazard material in the laboratory environment. Ability to sit for extended periods of time.
Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities long-term conditions mental health conditions or sincerely held religious beliefs. If you need support please reach out to
Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race color religion sex sexual orientation gender identity national origin or protected veteran status and will not be discriminated against on the basis of disability.
All your information will be kept confidential according to EEO guidelines.
To learn more about the information collected when you apply for a position at Guardant Health Inc. and how it is used please review our Privacy Notice for Job Applicants.
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Employment Type :
Full-time
Full-time