Senior Director, Clinical Pharmacology

Job Description

General Summary:

The Senior Director Clinical Pharmacology will serve as a Disease Area leader for Clinical Pharmacology. The Senior Director Clinical Pharmacology will also manage the scientific functions and coordinate the activities of the Clinical Pharmacology function in collaboration with the other Disease Area leaders. The roles responsibilities will include maintaining organizational processes across the group influencing clinical program strategy and integrating activities with other departments across the Global Research and Development organization to help shape innovative and integrated clinical development plans. As a Disease Area leader the Senior Director Clinical Pharmacology will also direct Clinical Pharmacology efforts for small molecule and novel modality programs such as gene editing gene therapy and cell therapy in the Disease Area.

Key Duties and Responsibilities:

• Defines the scientific direction and directs the execution of clinical pharmacology plans for Disease Area programs
• Provides strategic operational leadership to the Clinical Pharmacology function in collaboration with the other Disease Area Leaders
• Manages a group of Clinical Pharmacologists at Director-level and below to set strategy develop and execute Clinical Pharmacology plans and studies for Disease Area programs
• Directs Clinical Pharmacology efforts for small molecule and novel modality programs such as gene editing gene therapy and cell therapy in the Disease Area.
• As a people manager within the organization may have financial accountabilities and human resource responsibilities for assigned staff.

Knowledge and Skills:

• Experience designing clinical pharmacology and pharmacometrics components of filing packages and associated clinical studies
• Experience with regulatory agency interactions including written responses and IND packages
• Experience with Early Development Phase as well as End of Phase 2 and NDA/MAA regulatory
• Support of drug development programs in all Phases including life-cycle management
• Different therapeutic modality experience (large molecule small molecule etc.)
• Experience leading cross-functional teams
• Superior communication skills
• Ability to solve complex problems while working in a matrix environment
• Academic or clinical postdoctoral training with significant publication history

Education and Experience:

• Ph.D. or Pharm D (or equivalent degree) in pharmacokinetics pharmacometrics clinical pharmacology or translational development and 15 years of relevant post-doctoral employment experience or
• Masters Degree (or equivalent degree) in pharmacokinetics pharmacometrics clinical pharmacology or translational development and 20 years of relevant employment experience or
• Typically requires 5 years of supervisory/management experience

Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

In this Remote-Eligible role you can choose to be designated as:
1. Remote: work remotely five days per week and come into the office on occasion youre always welcome on-site; or select
2. Hybrid: work remotely up to two days per week; or select
3. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at