Postdoctoral Researcher
Postdoctoral Researcher
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Job Description
Union: Non-Union
Number of Vacancies: 1
Site: Princess Margaret Cancer Centre
Department: Research
Reports to: Principal Investigators Dr. Mohammad Mazhab-Jafari and Dr. Thomas Kislinger
Work Model: On site
Hours: 37.5 hours per week
Shifts: Day Shifts
Status: Temporary Full-time
Closing Date: June 9 2025
Position summary:
The Princess Margaret Cancer Centre a world-leading cancer research institution invites applications for a Postdoctoral Researcher position. The laboratories Thomas Kislinger and Mohammad Mazhab-Jafari are seeking a highly motivated and skilled scientist with expertise in mass spectrometry to join our cutting-edge research program. This position offers the opportunity to work at the forefront of cancer research exploring the intricate mechanisms of protein interactions and post-translational modifications in cancer biology.
The successful candidate will lead a project focused on studying fatty acid synthase (FASN) protein interactions and post-translational modifications (PTMs) across diverse cancer cell lines. Utilizing advanced affinity-purification mass spectrometry (AP-MS) techniques and cryo-electron microscopy (cryoEM) the project aims to provide deep insights into the role of FASN in cancer. The candidate will have access to state-of-the-art mass spectrometry and cryoEM instrumentation and will receive comprehensive training in these cutting-edge technologies.
Duties:
- Will be responsible for growing and maintaining cancer cell lines conducting affinity-purification experiments and performing mass spectrometry analyses to characterize protein interactions and modifications.
- Will analyze complex datasets to identify key biological insights (e.g. identify PTMs from AP-MS data).
- Collaborate with multidisciplinary teams to integrate findings
- Prepare high-quality manuscripts for publication in leading scientific journals.
- Participate in the mentoring of junior lab members.
- Additional responsibilities include presenting research findings at conferences.
Qualifications :
- PhD in Biochemistry Molecular Biology or a related field must be obtained within the previous 5 years.
- Expertise in mass spectrometry techniques particularly AP-MS.
- Experience in cell culturing techniques is preferred.
- Proficiency in data analysis and bioinformatics tools.
- Strong communication and organizational skills with the ability to work both independently and collaboratively.
- Familiarity with cryoEM is an asset but not required; training will be provided.
Additional Information :
Why join UHN
In addition to working alongside some of the most talented and inspiring healthcare professionals in the world UHN offers a wide range of benefits programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor allowing you to find value where it matters most to you now and throughout your career at UHN.
- Competitive offer packages
- Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP access to Transit and UHN shuttle service
- A flexible work environment
- Opportunities for development and promotions within a large organization
- Additional perks (multiple corporate discounts including: travel restaurants parking phone plans auto insurance discounts on-site gyms etc.)
Current UHN employees must have successfully completed their probationary period have a good employee record along with satisfactory attendance in accordance with UHNs attendance management program to be eligible for consideration.
All applications must be submitted before the posting close date.
UHN uses email to communicate with selected candidates. Please ensure you check your email regularly.
Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading inaccurate or incorrect UHN reserves the right to discontinue with the consideration of their application.
UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.
We thank all applicants for their interest however only those selected for further consideration will be contacted.
Remote Work :
No
Employment Type :
Contract
Employment Type
Contract
