Associate Director, PK Sciences Neuroscience Therapeutic Area
Associate Director, PK Sciences Neuroscience Therapeutic Area
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$ 145600 - 270400
1 Vacancy
Job Description
Band
Level 5Job Description Summary
#LI-HybridThis position will be on-site in Cambridge MA or East Hanover NJ and will not have the ability to be located remotely.
In the Associate Director in PK Sciences you will provide ADME /PK/PKPD project support to the Neuroscience Therapeutic Area contributing to projects from Discovery to IND filing and First-in-Human studies and beyond. In this unique role you will collaborate and partner with PK Sciences functions including in vitro and in vivo ADME biotransformation bioanalytics and modeling & simulation and represent the PK Sciences organization within project teams.
Job Description
Key Responsibilities:
- Support teams in developing the strategy for and coordinate the implementation of the characterization and selection of lead compounds and drug candidates with favorable PK/ADME properties elucidate PK/PD relationships driving efficacy/safety and contribute to human PK prediction and dose and regimen selection.
- Provide matrixed leadership across the organization to align and influence across the cross-functional team to identify and mitigate key project issues related to the pharmacokinetic sciences PKS discipline (PK PK/PD metabolism and clinical pharmacology).
- Proactively contribute to developing drug candidates across the Research Development and Commercial continuum providing expert pharmacokinetic / drug metabolism and clinical pharmacology input.
- Be responsible for the PK PK/PD and M&S component of study protocols reports project summaries and development plans and author pharmacokinetic/clinical pharmacology/biopharmaceutics sections of IND/IMPDs/NDAs/BLAs within agreed timelines and which meet regulatory requirements as well as prepare appropriate responses to Health Authority questions (globally).
- Oversee or perform PK and PK/PD analyses using a variety of tools and approaches and integrate interpret and report data to project teams and other customers. Our organization further offers the opportunity to seamlessly gain exposure to different stages of development different drug modalities and cross-train in multiple indications.
Essential Requirements:
- Ph.D. or Pharm.D. with relevant experience in clinical pharmacology drug metabolism and pharmacokinetics or a related biologic background.
- A minimum of 6 plus years in drug discovery or development function including 2 plus years of experience in a lead role overseeing ADME/DMPK or clinical pharmacology strategy of compound development.
- Extensive and in-depth knowledge of pharmacokinetics including drug metabolism and PK/PD evaluation experience in working in project teams (preferably global) as well as sound awareness of recent developments in drug development and regulatory sciences.
- Proficient in the application of PK and PK/PD analysis with working knowledge of software such as WINNONLIN/Phoenix
- Hands-on project experience with compounds of various modalities including low molecular weight and biologics drug discovery and development.
- Proven record as leader with good negotiation organizational and project management skills.
- Strong coaching and mentoring skills desired.
Novartis Compensation and Benefit Summary: The pay range for this position at commencement of employment is expected to be between: $145600 to $270400/year; however while salary ranges are effective from 1/1/25 through 12/31/25 fluctuations in the job market may necessitate adjustments to pay ranges during this period. Further final pay determinations will depend on various factors including but not limited to geographical location experience level knowledge skills and abilities. The total compensation package for this position may also include other elements including a sign-on bonus restricted stock units and discretionary awards in addition to a full range of medical financial and/or other benefits (including 401(k) eligibility and various paid time off benefits such as vacation sick time and parental leave) dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired employee will be in an at-will position and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.
EEO Statement:
The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment hiring training promotion or other employment practices for reasons of race color religion gender national origin age sexual orientation gender identity or expression marital or veteran status disability or any other legally protected status. We strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.
Accessibility and reasonable accommodations
The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If because of a medical condition or disability you need a reasonable accommodation for any part of the application process or in order to perform the essential functions of a position please send an e-mail to call 1 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.
Range
Skills Desired
Chemistry Clinical Pharmacology Clinical Research Clinical Study Reports Clinical Trials Data Entry Drug Discovery Due Diligence Electronic Components Gene Therapy Lifesciences Medical Research Microsoft Office Modeling And Simulation Patient Care Physics Translational Medicine Waterfall ModelRequired Experience:
Director
Employment Type
Full-Time
