Protein Sciences Senior Research Associate
Protein Sciences Senior Research Associate
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$ 69600 - 104400
1 Vacancy
Job Description
Job Description
Vertex Pharmaceuticals is seeking a highly motivated Senior Research Associate to join the Protein Sciences team in San Diego. The Protein Sciences team is responsible for guiding our drug discovery programs through key molecular insights that underlie disease target function and modulation. The successful candidate will support the advancement of our research programs to create transformative medicines for patients with serious diseases through the generation of high-quality recombinant proteins for biochemical biophysical and / or structural biology experiments.
KEY RESPONSIBILITIES:
- With minimal supervision perform hands-on expression purification and characterization of mammalian integral membrane proteins for assay development and biophysical experiments.
- Design and implement protein purification protocols to generate high quality homogeneous protein using various chromatography methods such as affinity size exclusion ion exchange.
- Seek out and implement alternative strategies to address potential challenges in protein expression and purification to ensure consistent deliveries of high-quality protein.
- Hands-on characterization of the stability and homogeneity of purified proteins using techniques such as FPLC HPLC SDS-PAGE LC-MS.
- Work collaboratively within the team as well as cross-functionally to achieve program goals.
- Excellent record keeping and compliance with Electronic Lab Notebook (ELN) submissions.
- An open mindset and eagerness to learn new techniques as needed.
EDUCATION AND EXPERIENCE:
- Masters Degree (or equivalent degree) in biological sciences and 0-2 years of relevant employment experience or
- Bachelors Degree (or equivalent degree) in biological sciences and 4 years of relevant employment experience
- Hands-on experience in purifying high-quality recombinant proteins for biochemistry biophysics or structural biology experiments.
- Hands-on experience in heterologous protein expression in mammalian and/or insect systems.
- Ability to multitask and attention to detail.
- Team oriented with the ability to work effectively in a fast-paced timeline-driven work environment.
- Strong communication skills (oral and written) in presenting results and objectives to the Protein Sciences team and to larger cross-functional teams.
#LI-SV1
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Pay Range:
$69600 - $104400Disclosure Statement:
The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors including skills competencies experience and other job-related factors permitted by law.
At Vertex our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career financial family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter) educational assistance programs including student loan repayment a generous commuting subsidy matching charitable donations 401(k) and so much more.
Flex Designation:
On-Site DesignatedFlex Eligibility Status:
In this On-Site designated role you will work five days per week on-site with ad hoc flexibility.
Note: The Flex status for this position is subject to Vertexs Policy on Flex @ Vertex Program and may be changed at any time.
Company Information
Vertex is a global biotechnology company that invests in scientific innovation.
Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a persons race color sex gender identity or expression age religion national origin ancestry ethnicity disability veteran status genetic information sexual orientation marital status or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities in accordance with applicable law.
Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager or contact Talent Acquisition at
Required Experience:
Senior IC
Employment Type
Full-Time
