Head of Antibody Drug Conjugates, Biologics Engineering

Head of Antibody Drug Conjugates Biologics Engineering

Locations: Gaithersburg MD/Waltham MA

Are you a visionary in drug development with a passion for pioneering new biologics Biologics Engineering is seeking a highly accomplished and innovative drug developer to join our team as a Head of Antibody Drug Conjugates. In this pivotal role you will be responsible for shaping the strategic direction of our Antibody Drug Conjugates and Radioconjugates therapeutics pipeline. Your expertise in protein engineering bioconjugation and nextgeneration ADC platform technologies will be instrumental in driving the development of the AstraZeneca portfolio of life changing medicines.

We are seeking a recognized leader and subject matter expert with a proven track record of contribution to the ADC clinical pipeline. Your role will involve spearheading the advancement of cuttingedge technologies leading a highperforming team and ensuring operational excellence to propel our next generation ADCs and RCs to new heights. If you are ready to make a profound impact on the future of targeted biologics drug delivery we invite you to
apply for this compelling opportunity at our stateoftheart laboratories in Gaithersburg MD.

What you will do

• Establish strategy direction and objectives for the development of nextgeneration ADC technologies
• Provide scientific leadership mentorship and technical guidance to a diverse team of scientists responsible for a robust ADC and RC biotherapeutics portfolio
• Drive innovation in ADC and RC across oncology and other therapeutic areas
• Act as a subject matter expert in Protein Engineering/Bioconjugation for targeted delivery modalities
• Represent Biologics Engineering in crossfunctional collaborations to accelerate the discovery of groundbreaking medicines
• Ensure the delivery of a rich pipeline of drug candidates and other Biologics Engineering organizational priorities
• Foster a culture of transparency innovation and creativity leading to new opportunities for the company and creation of intellectual property
• Partner with Business Development to pursue investments that enhance Biologics Engineering strategy
• Maintain a high degree of awareness of internal and external technology developments in the targeted delivery space
• Manage priorities resources growth and investments aligned with the Biologics Engineering strategy
• Attract and develop talent to strengthen the team

Basic Requirements:

• PhD in Biochemistry Protein Engineering or related scientific discipline
• 10 year of experience in building and leading highperforming ADC and Protein Engineering teams:
• Proven ability to think strategically act decisively collaborate
  effectively and drive team performance
• Extensive track record of advancing numerous ADC therapeutics from discovery to the clinic contributing to the pipeline of Big Pharma or major Biotech
• Recognized as a subject matter expert in nextgeneration ADC platform technologies protein and linker engineering sitespecific conjugation novel warhead development and utilization of diverse formats such as traditional and bispecific antibodies fragments and different protein scaffolds
• Strong external reputation as an industry leader evidenced by highimpact
  publications presentations and scientific community engagement
• Deep expertise in all aspects of ADC design nonclinical characterization and manufacturing
• Ability to advance projects against accelerated timelines define clear go/nogo decision points with a sharp focus on execution
• Exceptional communication skills highly effective in interacting with key internal and external stakeholders
• Demonstrated passion for and a track record of talent recruitment and development

The annual base salary for this position ranges from $208389$312. However base pay offered may vary depending on multiple individualized factors including market location jobrelated knowledge skills and experience. In addition our positions offer a shortterm incentive bonus opportunity; eligibility to participate in our equitybased longterm incentive program. Benefits offered included a qualified retirement program 401(k) plan; paid vacation and holidays; paid leaves; and health benefits including medical prescription drug dental and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired employee will be in an atwill position and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time including for reasons related to individual performance Company or individual department/team performance and market factors.

Why AstraZeneca:

At AstraZeneca were dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. Theres no better place to make a difference to medicine patients and society. An inclusive culture that champions diversity and collaboration. Always committed to lifelong learning growth and development.

When we put unexpected teams in the same room we unleash bold thinking with the power to inspire lifechanging medicines. Inperson working gives us the platform we need to connect work at pace and challenge perceptions. Thats why we work on average a minimum of three days per week from the office. But that doesnt mean were not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Date Posted

30Oct2024

Closing Date

24Nov2024Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion starting with our recruitment process. We welcome and consider applications from all qualified candidates regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations please complete the section in the application form.

AstraZeneca requires all US employees to be fully vaccinated for COVID19 but will consider requests for reasonable accommodations as required by applicable law.