Principle Scientist, Protein Engineering & Biotherapeutic Discovery
Principle Scientist, Protein Engineering & Biotherapeutic Discovery
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$ 102900 - 171500
1 Vacancy
Job Description
ROLE SUMMARY
Pfizers Biotherapeutic Discovery group in La Jolla is seeking an outstanding highly motivated and proven protein engineering expert. The candidate will be responsible for developing biologics with a primary focus on engineering nextgeneration biologics and hit identification/lead optimization of antibodies. Additionally the candidate will work closely with individuals in both protein engineering and biology groups to innovate and develop the next generation of protein therapeutics. The candidate will have access to stateoftheart protein and antibody engineering technologies and will be expected to continue our tradition of developing worldclass methods and technologies that enhance our therapeutic discovery efforts.
ROLE RESPONSIBILITIES
- Engage with therapeutic areas to design and apply new antibody MOAs at the interface of biology and molecular engineering.
- Carry out handson lab work to apply protein engineering principles to the generation of novel protein therapeutics.
- Conduct antibody discovery against challenging membrane targets.
- Work in teams to develop nextgeneration therapeutics and influence project teams in their decisionmaking.
- Stay informed with literature and scientific advancement in the biologics discovery and engineering field.
- Present experimental designs and results at internal and crossfunction team meetings.
BASIC QUALIFICATIONS
- Ph.D. in Biological Science (Structural Biology Protein Biochemistry Molecular Biology) required.
- Minimum 5 years postgraduate experience in academia or industry.
- Proven scientific achievements through publications or intellectual property.
- Extensive technical skills in protein expression purification molecular biology and structurefunction relationships.
- Proficient handson experience in protein/antibody engineering and structural biology.
- Strong understanding of antibody structure/sequence and antibody behavior/function relationship.
- Experience in antibody discovery projects.
- Innovative with a successful record in biologics design creative problemsolving and strong analytical skills.
- Collaborative scientist with broad interests diverse background and ability to work across disciplines.
- Excellent interpersonal collaborative and oral communication skills.
- Capable of analyzing and applying relevant published work.
PREFERRED QUALIFICATIONS
- Antibody discovery against difficult membrane targets.
- Expertise in membrane protein production.
- Motivated to understand biology and innovate new proteinbased therapeutics.
- Strategic thinking with an ability to understand program and therapeutic area needs and translate that understanding into an actionable approach.
Other Job Details:
- Last Date to Apply for Job: 22 MAY 2025
- Relocation support available
Work Location Assignment:On Premise
The annual base salary for this position ranges from $102900.00 to $171500.00. In addition this position is eligible for participation in Pfizers Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of lifes moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution paid vacation holiday and personal days paid caregiver/parental and medical leave and health benefits to include medical prescription drug dental and vision coverage. Learn more at Pfizer Candidate Site U.S. Benefits (). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care providers name address and the type of payments or other value received generally for public disclosure. Subject to further legal review and statutory or regulatory clarification which Pfizer intends to pursue reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse your name address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race color religion sex sexual orientation age gender identity or gender expression national origin disability or veteran status. Pfizer also complies with all applicable national state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an EVerify employer. This position requires permanent work authorization in the United States.
Employment Type
Full-Time
