Senior Research Associate
Senior Research Associate
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$ 114000 - 150000
1 Vacancy
Job Description
Cytokinetics is a latestage specialty cardiovascular biopharmaceutical company focused on discovering developing and commercializing firstinclass muscle activators and nextinclass muscle inhibitors as potential treatments for debilitating diseases in which cardiac muscle performance is compromised. As a leader in muscle biology and the mechanics of muscle performance the company is developing small molecule drug candidates specifically engineered to impact myocardial muscle function and contractility.
At Cytokinetics each team member plays an integral part in advancing our mission to improve the lives of patients. We are seeking tenacious compassionate and collaborative individuals who are driven to make a positive impact
We seek a highly motivated Research Associate to join our Discovery Biology group to help drive the early steps of our drug discovery efforts. Drug discovery and optimization will use a broad variety of novel biochemical and cellular approaches to identify compounds that improve cardiac and skeletal muscle contractility and metabolism. Innovative design and execution of experiments that facilitate the successful discovery of drugs that improve human health is our primary goal.
Responsibilities:
This candidate will play a key role in supporting lead optimization programs by developing and running biochemical and cellular assays for hit identification and lead optimization as well as mechanism of action studies and will work closely with cross functional teams.
The candidate will be involved in cell culture maintenance with other scientists within the department to support our preclinical drug discovery efforts in the areas of skeletal muscle and/or cardiac contractility and metabolism
The candidate will perform primary literature and genomic/metabolomic search to identify novel drug targets for future development
The candidate will use data analysis software to analyze large datasets generate integrated data analysis reports and provide results to stakeholders in a timely manner through written and verbal presentations.
As a member of a multidisciplinary team this person will work closely with team members to identify characterize and advance compounds through research and preclinical development.
Qualifications:
The position requires a BS or MS in cell biology molecular biology biochemistry physiology or related field with 2 plus years of research experience in an academia or 3 years of experience in pharmaceutical or biotechnology setting
Handson expertise with molecular and cell biology techniquesincluding qPCR western blotting and 2D and 3D cell culture models using hPSC lines and primary cellsis required
Experience in preparing histological slides for microscopic examination immunohistochemical staining fluorescence imaging and interpreting stained slides is required
Prior experience in biochemical and/or cellbased assay development and execution including data analysis and reporting is required
Working knowledge of cardiac and/or skeletal muscle biology and histology is preferred
Knowledge/experience with multiparameter FACS sorting and analysis is preferred
Handson expertise in rodentin vivoexperiments including dosing (IP/IV/PO) tissue collection etc. is preferred
Strong skills in data analysis and visualization (Excel and GraphPad is preferred)
An ability to multitask strong organizational and time management skills attention to detail and flexibility are required
Enthusiasm for working in a teambased multidisciplinary environment paired with excellent verbal and written communication skills is required
Pay Range:
In the U.S. the hiring pay range for fully qualified candidates is $114000$150000 per year. The base pay actually offered will take into account internal equity and also may vary depending on the candidates geographic region jobrelated knowledge skills and experience among other factors.Our employees come from different backgrounds and we celebrate those differences. We are looking for the best candidates for our open roles but do not expect applicants to meet every qualification in order to be considered. If you are excited about what you could accomplish at Cytokinetics and believe you can add value to our team we would love to hear from you.
Please review ourGeneral Data Protection Regulation (GDPR) policyPRIOR to applying.
Our passion is anchored in robust scientific thinking grounded in integrity and critical thinking. We keep the patient front and center in all we do all actions and decisions are in service of the patient and their caregivers. We champion integrity ethics doing the right thing and being our best selves.
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Cytokinetics is an Equal Opportunity Employer
Required Experience:
Senior IC
Employment Type
Full-Time
