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You will be updated with latest job alerts via email$ 163000 - 191500
1 Vacancy
About Summit:
Ivonescimab known as SMT112 is a novel potential firstinclass investigational
bispecific antibody combining the effects of immunotherapy via a blockade of PD1 with the antiangiogenesis effects associated with blocking VEGF into a single molecule. Ivonescimab displays unique cooperative binding to each of its intended targets with multifold higher affinity when in the presence of both PD1 and VEGF.
Summit has begun its clinical development of ivonescimab in nonsmall cell lung cancer (NSCLC) with three active Phase III trials:
HARMONi is a Phase III clinical trial which intends to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFRmutated locally advanced or metastatic nonsquamous NSCLC who have progressed after treatment with a 3rd generation EGFR TKI (e.g. osimertinib).
HARMONi3 is a Phase III clinical trial which is designed to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with firstline metastatic NSCLC.
HARMONi7 is a Phase III clinical trial which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with firstline metastatic NSCLC whose tumors have high PDL1 expression.
Ivonescimab is an investigational therapy that is not approved by any regulatory authority in Summits license territories including the United States and Europe. Ivonescimab was approved for marketing authorization in China in May 2024. Ivonescimab was granted Fast Track designation by the US Food & Drug Administration (FDA) for the HARMONi clinical trial setting.
Overview of Role:
Summit Therapeutics is seeking a Managed Care Liaison (MCL) to join our mission of developing Ivonescimab a novel and unique immunotherapy with the potential to help patients suffering from lifethreatening cancers.
The Managed Care Liaison (MCL) is a critical member of an expanding team responsible for interfacing with US populationbased decision makers (PBDMs) including payers health systems clinical pathway organizations P&T committees and policy makers. The MCL educates key stakeholders on clinical economic and humanistic impact of ivonescimab to help inform formulary access pathway/guideline decisions and improve lives of cancer patients. Providing objective and scientifically sound medical information on ivonescimab and the relevant disease states through use of economic models outcomes tools educational programs and collaborations to enhance key stakeholder recognition of Summit Therapeutics. The MCL will compliantly partner with the commercial market access field team to facilitate access to ivonescimab through proactive engagement with organized customers ensuring the delivery of accurate nonpromotional medical information.
Role and Responsibilities:
Experience Education and Specialized Knowledge and Skills:
The pay range for this role is $163000$191500 annually. Actual compensation packages are based on several factors that are unique to each candidate including but not limited to skill set depth of experience certifications and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus stock benefits and/or other applicable variable compensation.
Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summits Talent Acquisition team at to obtain prior written authorization before referring any candidates to Summit.
Full-Time