Lead Researcher in Blue Sky Protein Kinases
Lead Researcher in Blue Sky Protein Kinases
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$ 60320 - 105040
1 Vacancy
Job Description
Join an excellent team of researchers dedicated to coming closer to the mission of St. Jude Childrens Research Hospital that no child will die at the dawn of life. The Kalodimos Lab at St. Jude Childrens Research Hospital is seeking a highly skilled and motivated Lead Researcher to join our prestigious Blue Sky Kinase Project. Led by Dr. Charalampos Kalodimos and supported by Dr. Madan Babu and Dr. Christoph Gorgulla this exciting initiative is funded by over $50 million providing exceptional resources and research conditions.
The successful candidate will have the opportunity to contribute to highly collaborative projects expand their skillsets and participate in highimpact publications. Collaboration is at the heart of our work and you will closely work with our computational and other wetlab colleagues to validate and experimentally verify the predicted hit and lead compounds. By working together in a collaborative and intellectually stimulating environment you will have the opportunity to contribute to multiple ligand/drug discovery projects and make a lasting impact on the lives of children fighting cancer and other lifethreatening diseases.
Job Responsibilities:
The successful candidate will play an active role in designing and developing biochemical and biophysical assays to support small molecule hit identification and MOA studies.
The candidate will carry out highthroughput assays for Hit identification and will help characterize the identified inhibitors using biochemical biophysical and cellular tools. The postdoc will have the opportunity to interact with multiple teams and experts within St. Jude to streamline hit identification using lab automation and stateofthe art cellular and biochemical tools and for carrying out assays for developing SAR and lead optimization for novel Kinase inhibitors.
Ideal Candidate:
The Successful candidate for this position will have a PhD in Biophysics or Biochemistry or Structure Biology. The candidate should demonstrate an academic record of excellence and a strong interest in the fields of ligand and drug discovery targeting Kinases.
Experience in ligand/drug discovery or structural biology is highly desired and . Interest in extending the candidates skill set in these areas would be valuable.
Lead Researcher:
- Bachelors degree in a relevant scientific area is required.
Minimum Experience:
- 5 (five) years of experience with a Bachelors degree.
- 2 (two) years of experience with a Masters degree.
- no additional experience with a PhD.
About St. Jude
St. Jude Childrens Research Hospital is a worldclass research institution dedicated to pediatric cancer and other catastrophic diseases of childhood. The first and only National Cancer Institute (NCI)designated Comprehensive Cancer Center devoted solely to children. Our 300 faculty work across the spectrum of basic translational clinical and population science in a highly collaborative multidisciplinary environment that includes a Nobel laureate and members of the National Academy of Science and the National Academy of Medicine. St. Jude is ranked on Fortune Magazines Best Workplaces in Health Care & Biopharma and Glassdoors Best Places to Work. St. Jude is one of the bestfunded research institutes in the US with an annual budget of over $2 billion per year ( at St. Jude is a remarkable and special experience in many ways.
Mission: At St. Jude working is more than just a job its a calling. Each member of St. Jude is united by a shared purpose: finding cures and saving children. In addition to the meaningful work you will undertake we offer a range of perks to enhance your experience.
Community and Belonging: St. Jude is like a warm family that welcomes you to a large part because it is a Childrens hospital. It provides an exceptionally warm and friendly atmosphere. St. Jude also fosters a vibrant scientist and postdoc community that supports a wellbalanced life. A dynamic environment promotes connections and camaraderie among researchers from all backgrounds
The Best of Both Worlds Industry and Academia: St. Jude provides academic freedom in research and industrial efficiency and resources. We have access to worldclass shared resources/facilities led by expert scientists coupled with stateoftheart technology and funding accelerating research productivity.
Benefits: St. Jude offers a worldclass benefits package ( Enjoy comprehensive healthcare a competitive salary tuition assistance for continued education and exceptional worklife balance with ample paid time off.
Additional Perks: St. Jude offers many special perks such as an onsite gym an employee pharmacy and many others. To learn more about the unexpected perks of working at St. Jude visit our website at and Career Growth: Experience specifically designed programs to enhance professional growth and career readiness empowering postdocs for success beyond their training. This includes access to grant writing workshops individual development plans teaching and mentoring opportunities nonresearch career advancement programs professional development allowance and so much more. More information can be found at St. Jude is dedicated to fostering an inclusive and diverse scientific community where everyones contributions are valued. St. Jude Childrens Research Hospital has a diverse global patient population and workforce built on the principles of diversity equity and inclusion. Our founder Danny Thomas envisioned a hospital that would treat children of the worldregardless of race religion or a familys ability to pay. Learn more about our history and commitment. Today we continue the mission to advance cures and means of prevention for pediatric catastrophic diseases through research and treatment. As we accelerate this progress globally we believe our legacy of diversity equity and inclusion is foundational to success. With the commitment of leaders at all levels of the organization we strive to ensure the St. Jude culture leadership approaches and talent processes are equitable and culturally responsive. More information is available here.
Competitive Compensation: Embark on your journey with a competitive salary (depending on experience) comprehensive benefits and generous relocation assistance reflecting our commitment to recognize and invest in talent. Furthermore in Memphis/Tennessee there is no income tax.
Top Employer: St. Jude was among the top 10 large employers in the US in 2024 ahead of Google Microsoft and Apple: Employer for Women: St. Jude is also among the top 10 employers for women in the US: Jude Childrens Research Hospital is high school and college students top dream employer according to the National Society of High School Scholars (NSHSS) 2018 Career Interest Survey. Memphis
St. Jude is located in the heart of Memphis Tennessee a vibrant and friendly city at the historic American crossroads of music trade food and culture. Living in Memphis provides several unique advantages including:
Breathtaking Nature: Memphis provides unique nature and scenery such as the Mississippi (the largest river in the US) or Shelby Farms Park with which 4500 acres is one of the largest urban parks in the country. See for more details.
Its Culture: It is for instance the home of Elvis Presley. See for more details on the cultural aspects.
Its Affordability: Memphis is one of the most affordable cities in the US meaning the same income will bring you farther than in other places in the US (for more details see In addition there is no income tax in Tennessee.
Compensation
In recognition of certain U.S. state and municipal pay transparency laws St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets experience and training licensure and certifications and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $60320 $105040 per year for the role of Lead Researcher in Blue Sky Protein Kinases.Explore our exceptional benefits!
No Search Firms
St. Jude Childrens Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.
Employment Type
Full-Time
