Senior/Staff Scientist, Chemistry
Senior/Staff Scientist, Chemistry
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USD 120000 - 183000
1 Vacancy
Job Description
About Glyphic:
At Glyphic Biotechnologies we plan to create the protein revolution for which scientists and researchers have been waiting. We are developing a massively parallel singlemolecule proteome sequencing platform that will transform life science discovery and usher in a new era of insights into human biology and disease. To date we have raised >$50M from venture partners and nondilutive grant funding to achieve our vision of next generation proteome sequencing.
What we are looking for in you:
Glyphic is seeking a highly motivated and experienced Scientist to join the Chemistry Department to assist in the advancement of our cuttingedge single molecule proteome sequencing platform.
The ideal candidate will have a strong background in nucleic acid & protein chemistry bioconjugation analytical instrumentation and be eager to contribute to transformative advances in proteomics. The scientist will work with a crossdisciplinary team of scientists engineers and bioinformaticians to rapidly deliver consistent results and insights that accelerate the development cycle.
Responsibilities:
Design develop and optimize high throughput chemical reagent evaluation for single molecule protein sequencing ensuring high sensitivity specificity and reproducibility
Synthesize assay specific reagents and materials for the proteome sequencing platform
Develop and/or validate peptide sample preparation schemes such as Cterminal conjugation and amino acid sidechain derivatization
Collaborate with crossfunctional teams to problem solve and integrate novel solutions into the assay workflow
Analyze complex experimental data generate detailed reports and provide actionable insights to guide further development
Utilize statistical methods and data visualization tools to interpret assay performance and ensure rigorous quality control
Prepare and maintain comprehensive documentation of experimental protocols standard operating procedures (SOPs) and results
Drive innovation in reagent and compound synthesis and design and contribute to intellectual property development
Required Competencies:
PhD in chemistry organic chemistry or related field with 5 years of relevant experience in an industrial or startup setting
Comprehensive knowledge in bioconjugation and biorthogonal conjugation methods and techniques
Competence in peptide Cterminal conjugation chemistry
Experience with nucleic acid and peptide synthesis natural and synthetic analogs
Experience in multistep smallscale organic synthesis particularly from complex biological matrices or samples
Analytical experience with HPLC LC/MS NMR FTIR UV/VIS CE
Proficiency in scalable surface chemistry methods and techniques for flow cells and/or solid supports
Experience inthe development of commercial products a plus
Excellent problemsolving skills and attention to detail
Strong written and verbal communication skills with the ability to document experiments clearly and collaborate effectively with multidisciplinary teams
Experience in data analysis software
Experience instatistical and DOE software
Adapts to fastpaced environments with changing priorities and responsibilities
Benefits and Perks:
Employee Stock Option Plan
100% Health Plan Coverage for Employees & Dependents (Medical Dental & Vision)
Employer Retirement Contributions to 401(k)
Generous Paid Time Off
Paid Maternity and Paternity Leave
Health & Wellbeing Program
Office Snacks and Beverages
Regular Team Bonding Activities
We are an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. Individuals seeking employment at Glyphic Biotechnologies are considered without regard to race color religion national origin age sex marital status ancestry physical or mental disability veteran status gender identity or sexual orientation.
Required Experience:
Staff IC
Employment Type
Full-Time
